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Substance Name: Phosphoribosylaminoimidazolecarboxamide Formyltransferase
RN: 9032-03-5


  • An enzyme that catalyzes the conversion of aminoimidazole-4-carboxamide ribonucleotide to 5-formyl-aminoimidazole-4-carboxamide ribonucleotide in the purine de novo synthesis pathway. It requires the cofactor N(10)-FORMYLTETRAHYDROFOLATE as the formyl donor.
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Names and Synonyms

Name of Substance

  • Phosphoribosylaminoimidazolecarboxamide Formyltransferase

MeSH Heading

  • Phosphoribosylaminoimidazolecarboxamide Formyltransferase


  • AICAR Formyltransferase
  • AICAR Transformylase
  • AICARTFase
  • Aminoimidazolecarboxamide Ribonucleotide Transformylase
  • Formyltransferase, AICAR
  • Formyltransferase, Phosphoribosylaminoimidazolecarboxamide
  • Ribonucleotide Transformylase, Aminoimidazolecarboxamide
  • Transformylase, AICAR
  • Transformylase, Aminoimidazolecarboxamide Ribonucleotide

Systematic Name

  • 5-amino-4-imidazolecarboxamide ribotide transformylase

Registry Numbers

CAS Registry Number

  • 9032-03-5

System Generated Number

  • 0009032035