Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Cholesterol 7-alpha-Hydroxylase
RN: 9037-53-0

Note

  • A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS.
 
* denotes mobile formatted website

Links to Resources

Names and Synonyms

Name of Substance

  • Cholesterol 7-alpha-Hydroxylase

MeSH Heading

  • Cholesterol 7-alpha-Hydroxylase

Synonyms

  • Cholesterol 7 alpha Hydroxylase
  • Cholesterol 7 alpha Monooxygenase
  • Cholesterol 7 Hydroxylase
  • Cholesterol 7-alpha-Monooxygenase
  • Cholesterol 7alpha Hydroxylase
  • Cholesterol 7alpha-Hydroxylase
  • Cholesterol-7-Hydroxylase
  • CYP 7
  • CYP 7A
  • CYP7
  • CYP7A
  • Cytochrome P 450 CYP7
  • Cytochrome P-450 CYP7
  • Cytochrome P450 7

Systematic Name

  • Cholesterol,NADPH:oxygen oxidoreductase (7 alpha-hydroxylating)

Registry Numbers

CAS Registry Number

  • 9037-53-0

System Generated Number

  • 0009037530