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Substance Name: Hydroxypropylmethylcellulose phthalate [JAN]
RN: 9050-31-1

Note

  • Used to coat microgranules.

Classification Code

  • TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)

Molecular Formula

  • C8-H6-O4.x-C3-H8-O2.x-C-H4-O.x-Unspecified

Molecular Weight

  • 780.725
 
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Names and Synonyms

Name of Substance

  • Hydroxypropyl methylcellulose phthalate
  • Hydroxypropylmethylcellulose phthalate [JAN]

Synonyms

  • 2-Hydroxypropyl methyl cellulose phthalate
  • Cellulose phthalate hydroxypropyl methyl ether
  • HP 55
  • HP 55 F
  • Hpmcp
  • Hydroxypropylmethylcellulose phthalate
  • UNII-87Y6436BKR
  • UNII-8LDD2V82F5
  • UNII-G4U024CQK6

Systematic Name

  • Cellulose, hydrogen 1,2-benzenedicarboxylate, 2-hydroxypropyl methyl ether

Registry Numbers

CAS Registry Number

  • 9050-31-1

FDA UNIIs

  • 87Y6436BKR
  • 8LDD2V82F5
  • G4U024CQK6

Other Registry Numbers

  • 168395-88-8
  • 37324-31-5
  • 42612-68-0
  • 52624-22-3
  • 9087-42-7

System Generated Number

  • 0009050311

Molecular Formulas

Molecular Formula

  • C8-H6-O4.x-C3-H8-O2.x-C-H4-O.x-Unspecified

Molecular Formula Fragments

  • C-H4-O
  • C3-H8-O2
  • C8-H6-O4
  • COMPONENT
  • Unspecified

Structure Descriptors

Smiles

O([C@H]1[C@@H]([C@H]([C@H](O*)O[C@@H]1COC(C)(C)O)OC(c1c(cccc1)C(O)=O)=O)OC)[C@H]1[C@@H]([C@H]([C@H](O*)[C@H](O1)COC(C)(C)O)OC(c1c(cccc1)C(O)=O)=O)OC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD oral > 15gm/kg (15000mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1017, 1970.