Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Pevonedistat [USAN:INN]
RN: 905579-51-3
UNII: S3AZD8D215
InChIKey: MPUQHZXIXSTTDU-QXGSTGNESA-N

Note

  • A potent and selective inhibitor of NAE (NEDD8-activating enzyme).

Classification Code

  • Enzyme Inhibitors

Molecular Formula

  • C21-H25-N5-O4-S

Molecular Weight

  • 443.5255
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Pevonedistat
  • Pevonedistat [USAN:INN]

Synonyms

  • ((1S,2S,4R)-4-(4-((1S)-2,3-Dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulphamate
  • MLN 4924
  • MLN4924
  • Pevonedistat
  • UNII-S3AZD8D215

Systematic Name

  • Sulfamic acid, ((1S,2S,4R)-4-(4-(((1S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl ester

Registry Numbers

CAS Registry Number

  • 905579-51-3

FDA UNII

  • S3AZD8D215

System Generated Number

  • 0905579513

Structure Descriptors

InChI

1S/C21H25N5O4S/c22-31(28,29)30-11-14-9-15(10-19(14)27)26-8-7-17-20(23-12-24-21(17)26)25-18-6-5-13-3-1-2-4-16(13)18/h1-4,7-8,12,14-15,18-19,27H,5-6,9-11H2,(H2,22,28,29)(H,23,24,25)/t14-,15+,18-,19-/m0/s1

InChIKey

MPUQHZXIXSTTDU-QXGSTGNESA-N

Smiles

c1ccc2c(c1)CC[C@@H]2Nc3c4ccn(c4ncn3)[C@@H]5C[C@H]([C@H](C5)O)COS(=O)(=O)N