Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Timolol [USAN:INN:BAN]
RN: 91524-16-2
UNII: 817W3C6175
InChIKey: RFBICEPZZKOQIA-OBPBZEKASA-N

Note

  • A beta-adrenergic antagonist similar in action to PROPRANOLOL. The levo-isomer is the more active. Timolol has been proposed as an antihypertensive, antiarrhythmic, antiangina, and antiglaucoma agent. It is also used in the treatment of MIGRAINE DISORDERS and tremor.

Molecular Formula

  • C13-H24-N4-O3-S.1/2H2-O

Molecular Weight

  • 649.8541
 

Classification Codes

  • Adrenergic Agents
  • Adrenergic Antagonists
  • Adrenergic beta-Antagonists
  • Anti-Adrenergic (beta-Receptor)
  • Anti-Arrhythmia Agents
  • Antihypertensive Agents
  • Cardiovascular Agents
  • Neurotransmitter Agents

Names and Synonyms

Name of Substance

  • Timolol [USAN:INN:BAN]

MeSH Heading

  • Timolol

Synonyms

  • (S)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)-2-propanol hemihydrate
  • 2-Propanol, 1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-, hemihydrate, (S)-
  • Betimol
  • Timolol
  • UNII-817W3C6175

Systematic Name

  • 2-Propanol, 1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-, hemihydrate, (S)-

Registry Numbers

CAS Registry Number

  • 91524-16-2

FDA UNII

  • 817W3C6175

System Generated Number

  • 0091524162

Molecular Formulas

Molecular Formula

  • C13-H24-N4-O3-S.1/2H2-O

Molecular Formula Fragments

  • C13-H24-N4-O3-S
  • COMPONENT
  • H2-O

Structure Descriptors

InChI

1S/C26H47N8O6S2.H2O/c1-25(2,3)27-13-18(35)15-38-23-21(29-41-31-23)33-8-11-40(12-9-33)20-17-37-10-7-34(20)22-24(32-42-30-22)39-16-19(36)14-28-26(4,5)6;/h18-20,27-28,35-36H,7-17H2,1-6H3;1H2/t18-,19-,20?;/m0./s1

InChIKey

RFBICEPZZKOQIA-OBPBZEKASA-N

Smiles

O.CC(C)(C)NC[C@H](O)COc1nsnc1N2CC[O](CC2)C3COCCN3c4nsnc4OC[C@@H](O)CNC(C)(C)C