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Substance Name: Cefdinir [USAN:USP:INN:BAN]
RN: 91832-40-5
UNII: CI0FAO63WC
InChIKey: RTXOFQZKPXMALH-GHXIOONMSA-N

Note

  • Synthetic antibiotic.

Molecular Formula

  • C14-H13-N5-O5-S2

Molecular Weight

  • 395.4187
 

Classification Codes

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antibacterial
  • Reproductive Effect

Names and Synonyms

Name of Substance

  • Cefdinir
  • Cefdinir [USAN:USP:INN:BAN]

Synonyms

  • (-)-(6R,7R)-7-(2-(2-Amino-4-thiazolyl)glyoxylamido)-8-oxo-3-vinyl-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7(sup 2)-(Z)-oxime
  • BMY 28488
  • Cefdinir
  • Cefdinirum
  • Cefdinirum [INN-Latin]
  • Cefdinyl
  • Ceftinex
  • CI-983
  • FK 482
  • Omnicef
  • UNII-CI0FAO63WC

Systematic Names

  • 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl) (hydroxyimino)acetyl)amino)-3-ethenyl-8-oxo-, (6R-(6alpha,7beta(Z)))-
  • 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(hydroxyiminoacetyl)amino)-3-ethenyl-8-oxo-, (6R-(6-alpha,7-beta(Z)))-

Superlist Name

  • CI 983

Registry Numbers

CAS Registry Number

  • 91832-40-5

FDA UNII

  • CI0FAO63WC

System Generated Number

  • 0091832405

Structure Descriptors

InChI

1S/C14H13N5O5S2/c1-2-5-3-25-12-8(11(21)19(12)9(5)13(22)23)17-10(20)7(18-24)6-4-26-14(15)16-6/h2,4,8,12,24H,1,3H2,(H2,15,16)(H,17,20)(H,22,23)/b18-7-/t8-,12-/m1/s1

InChIKey

RTXOFQZKPXMALH-GHXIOONMSA-N

Smiles

Nc1nc(cs1)\C(=N\O)\C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)O)C=C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 1gm/kg (1000mg/kg)   Drugs in Japan Vol. -, Pg. 667, 1995.
mouse LD50 intraperitoneal > 5600mg/kg (5600mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 93, 1992.
mouse LD50 intravenous > 2gm/kg (2000mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 93, 1992.
mouse LD50 oral > 5600mg/kg (5600mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 93, 1992.
mouse LD50 subcutaneous > 5600mg/kg (5600mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 93, 1992.
rat LD50 intraperitoneal > 5600mg/kg (5600mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 93, 1992.
rat LD50 intravenous > 2gm/kg (2000mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 93, 1992.
rat LD50 oral > 5600mg/kg (5600mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 93, 1992.
rat LD50 subcutaneous > 5600mg/kg (5600mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 93, 1992.