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Substance Name: 4-Biphenylamine
RN: 92-67-1
UNII: 16054949HJ
InChIKey: DMVOXQPQNTYEKQ-UHFFFAOYSA-N

Note

  • Used in detection of sulfates, & as a carcinogen in cancer research.

Molecular Formula

  • C12-H11-N

Molecular Weight

  • 169.226
 

Classification Codes

Classification Codes

  • Agricultural Chemical
  • Carcinogens
  • Fungicide, Bactericide, Wood Preservative
  • Mutation Data
  • Noxae
  • Tumor Data

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 232
  • 2011 CERCLA Priority List, Rank: 228
  • Known to be a Carcinogen
  • Overall Carcinogenic Evaluation: Group 1
  • Reportable Quantity (RQ) = 1 lb
  • Skin, Confirmed Human Carcinogen, Exposure by All Routes Should be Carefully Controlled to Levels as Low as Possible
  • TWA see 1910.1011

Names and Synonyms

Name of Substance

  • 4-Biphenylamine

Synonyms

  • (1,1'-Biphenyl)-4-amine
  • 4-12-00-03241 (Beilstein Handbook Reference)
  • 4-Amino-1,1'-biphenyl
  • 4-Aminobifenyl
  • 4-Aminobifenyl [Czech]
  • 4-Aminobiphenyl
  • 4-Aminodifenil
  • 4-Aminodifenil [Spanish]
  • 4-Aminodiphenyl
  • 4-Bifenylamin
  • 4-Bifenylamin [Czech]
  • 4-Biphenylamine
  • 4-Biphenylylamine
  • 4-Phenylaniline
  • AI3-00124
  • Aniline, p-phenyl-
  • Biphenylamine
  • BRN 0386533
  • CCRIS 26
  • EINECS 202-177-1
  • HSDB 1325
  • NSC 7660
  • p-Aminobiphenyl
  • p-Aminodiphenyl
  • p-Biphenylamine
  • p-Phenylaniline
  • p-Xenylamine
  • Paraaminodiphenyl
  • UNII-16054949HJ
  • Xenylamin
  • Xenylamin [Czech]
  • Xenylamine

Systematic Names

  • (1,1'-Biphenyl)-4-amine
  • 4-Aminobiphenyl
  • 4-Aminodiphenyl
  • 4-Biphenylamine
  • Biphenyl-4-ylamine

Superlist Names

  • (1,1'-Biphenyl)-4-amine
  • 4-Aminobiphenyl
  • 4-Aminodiphenyl

Registry Numbers

CAS Registry Number

  • 92-67-1

FDA UNII

  • 16054949HJ

Related Registry Number

  • 2113-61-3 (hydrochloride)

System Generated Number

  • 0000092671

Structure Descriptors

InChI

1S/C12H11N/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9H,13H2

InChIKey

DMVOXQPQNTYEKQ-UHFFFAOYSA-N

Smiles

c1(c2ccccc2)ccc(N)cc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo oral 25mg/kg (25mg/kg) BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN Science. Vol. 167, Pg. 992, 1970.
mouse LD50 oral 205mg/kg (205mg/kg)   European Journal of Cancer and Clinical Oncology. Vol. 21, Pg. 865, 1985.
mouse LDLo intraperitoneal 250mg/kg (250mg/kg) BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
"Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 6, Pg. 54, 1954.
rabbit LD50 oral 690mg/kg (690mg/kg)   Journal of Industrial Hygiene and Toxicology. Vol. 29, Pg. 1, 1947.
rabbit LD50 oral 690mg/kg (690mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: COMA
Journal of Industrial Hygiene and Toxicology. Vol. 29, Pg. 1, 1947.
rat LD50 oral 500mg/kg (500mg/kg) BEHAVIORAL: COMA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Industrial Hygiene and Toxicology. Vol. 29, Pg. 1, 1947.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 53.5 deg C   EXP
Boiling Point 302 deg C   EXP
pKa Dissociation Constant 4.35 (none) 18 EXP
log P (octanol-water) 2.86 (none)   EXP
Water Solubility 224 mg/L 25 EST
Vapor Pressure 1.17E-04 mm Hg 25 EST
Henry's Law Constant 1.46E-07 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 8.03E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.