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Substance Name: RAF 265
RN: 927880-90-8
UNII: 8O434L3768
InChIKey: YABJJWZLRMPFSI-UHFFFAOYSA-N

Note

  • B-Raf/VEGFR-2 inhibitor.

Molecular Formula

  • C24-H16-F6-N6-O

Molecular Weight

  • 518.4194
 
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Names and Synonyms

Results Name

  • RAF 265

Name of Substance

  • RAF265

Synonyms

  • CHIR 265
  • CHIR-265
  • RAF 265
  • UNII-8O434L3768

Systematic Name

  • 1H-Benzimidazol-2-amine, 1-methyl-5-((2-(5-(trifluoromethyl)-1H-imidazol-2-yl)-4-pyridinyl)oxy)-N-(4-(trifluoromethyl)phenyl)-

Registry Numbers

CAS Registry Number

  • 927880-90-8

FDA UNII

  • 8O434L3768

Other Registry Number

  • 937178-31-9

System Generated Number

  • 0927880908

Structure Descriptors

InChI

1S/C24H16F6N6O/c1-36-19-7-6-15(10-17(19)34-22(36)33-14-4-2-13(3-5-14)23(25,26)27)37-16-8-9-31-18(11-16)21-32-12-20(35-21)24(28,29)30/h2-12H,1H3,(H,32,35)(H,33,34)

InChIKey

YABJJWZLRMPFSI-UHFFFAOYSA-N

Smiles

Cn1c(Nc2ccc(cc2)C(F)(F)F)nc3cc(Oc4ccnc(c4)c5ncc([nH]5)C(F)(F)F)ccc13