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Substance Name: N,N-Diethyl-p-phenylenediamine
RN: 93-05-0
UNII: 0QQA4DFV2J
InChIKey: QNGVNLMMEQUVQK-UHFFFAOYSA-N

Classification Codes

  • Human Data
  • Mutation Data
  • Skin / Eye Irritant

Molecular Formula

  • C10-H16-N2

Molecular Weight

  • 164.25
 
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Names and Synonyms

Name of Substance

  • N,N-Diethyl 4-phenylenediamine
  • N,N-Diethyl-p-phenylenediamine

Synonyms

  • 1,4-Benzenediamine, N,N-diethyl-
  • 4-(Diethylamino)aniline
  • 4-Amino-N,N-diethylaniline
  • CCRIS 4620
  • Diethyl-p-phenylenediamine
  • Diethyl-para-phenylenediamine
  • Diethylaminoaniline
  • EC 202-214-1
  • EINECS 202-214-1
  • HSDB 5281
  • N,N-Diethyl-1,4-benzenediamine
  • N,N-Diethyl-4-aminoaniline
  • N,N-Diethyl-p-phenylenediamine
  • N,N-Diethyl-para-phenylenediamine
  • NSC 147488
  • p-(Diethylamino)aniline
  • p-Amino-N,N-diethylaniline
  • p-Aminodiethylaniline
  • p-Phenylenediamine, N,N-diethyl-
  • para-Aminodiethylaniline
  • UNII-0QQA4DFV2J

Systematic Names

  • 1,4-Benzenediamine, N,N-diethyl-
  • 1,4-Benzenediamine, N1,N1-diethyl-
  • 4-Amino-N,N-diethylaniline
  • N,N-Diethyl-p-phenylenediamine
  • p-Phenylenediamine, N,N-diethyl-

Superlist Name

  • Diethyl-p-phenylenediamine

Registry Numbers

CAS Registry Number

  • 93-05-0

FDA UNII

  • 0QQA4DFV2J

Related Registry Numbers

  • 16713-15-8 (unspecified hydrochloride)
  • 2198-58-5 (mono-hydrochloride)
  • 6065-27-6 (unspecified sulfate)
  • 62637-92-7 (oxalate[2:1])
  • 6283-63-2 (sulfate[1:1])

System Generated Number

  • 0000093050

Structure Descriptors

InChI

1S/C10H16N2/c1-3-12(4-2)10-7-5-9(11)6-8-10/h5-8H,3-4,11H2,1-2H3

InChIKey

QNGVNLMMEQUVQK-UHFFFAOYSA-N

Smiles

c1(N(CC)CC)ccc(N)cc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo oral 300mg/kg (300mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
dog LDLo intravenous 70mg/kg (70mg/kg)   Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
guinea pig LDLo subcutaneous 200mg/kg (200mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
human TDLo skin 73ug/kg (0.073mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER TOPICAL EXPOSURE"

BLOOD: HEMORRHAGE

SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
mouse LD50 oral 200mg/kg (200mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: FOOD INTAKE (ANIMAL)
National Technical Information Service. Vol. OTS,
mouse LDLo intraperitoneal 25mg/kg (25mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

SKIN AND APPENDAGES (SKIN): HAIR: OTHER

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
National Technical Information Service. Vol. OTS,
rabbit LDLo oral 450mg/kg (450mg/kg) BEHAVIORAL: COMA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
rabbit LDLo skin 125mg/kg (125mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: GENERAL ANESTHETIC
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
rabbit LDLo subcutaneous 250mg/kg (250mg/kg) BEHAVIORAL: COMA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
rat LD50 intraperitoneal 25mg/kg (25mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: TREMOR
National Technical Information Service. Vol. OTS,
rat LD50 oral > 200mg/kg (200mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: MUSCLE WEAKNESS
National Technical Information Service. Vol. OTS,
rat LDLo subcutaneous 100mg/kg (100mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: COMA
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Boiling Point 261 deg C   EXP
pKa Dissociation Constant 7.96 (none)   EXP
log P (octanol-water) 2.240 (none)   EST
Water Solubility 806 mg/L 25 EST
Vapor Pressure 2.98E-03 mm Hg 25 EST
Henry's Law Constant 5.33E-08 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.18E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.