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Substance Name: Rimabotulinumtoxinb [USAN]
RN: 93384-44-2
UNII: 0Y70779M1F

Note

  • A neuromuscular agent used for the treatment of cervical dystonia.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Acetylcholine Release Inhibitors
  • Anti-Dyskinesia Agents
  • Central Nervous System Agents
  • Cholinergic Agents
  • Membrane Transport Modulators
  • Natural Product
  • Neurotransmitter Agents
  • Treatment of Cervical Dystonia

Names and Synonyms

Name of Substance

  • RimabotulinumtoxinB
  • Rimabotulinumtoxinb [USAN]

Synonyms

  • AN0772
  • Botulin B
  • Botulin toxin B
  • BTX-B
  • EINECS 297-255-5
  • Myobloc
  • NeuroBloc
  • Rimabotulinumtoxinb
  • UNII-0Y70779M1F

Systematic Names

  • Botulin B
  • Toxins, botulin, B

Registry Numbers

CAS Registry Number

  • 93384-44-2

FDA UNII

  • 0Y70779M1F

System Generated Number

  • 0093384442

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
domestic animals - goat/sheep LDLo oral 34mg/kg (34mg/kg)   Annales de l'Institut Pasteur Vol. 72, Pg. 545, 1946.
guinea pig LDLo subcutaneous 5ug/kg (0.005mg/kg)   Annales de l'Institut Pasteur Vol. 71, Pg. 490, 1945.
rabbit LDLo intramuscular 50mg/kg (50mg/kg)   Annales de l'Institut Pasteur Vol. 71, Pg. 490, 1945.
rabbit LDLo intraperitoneal 50mg/kg (50mg/kg)   Annales de l'Institut Pasteur Vol. 71, Pg. 490, 1945.
rabbit LDLo intravenous 5ug/kg (0.005mg/kg)   Annales de l'Institut Pasteur Vol. 71, Pg. 490, 1945.
rabbit LDLo oral 50mg/kg (50mg/kg)   Annales de l'Institut Pasteur Vol. 71, Pg. 490, 1945.
rabbit LDLo rectal 50mg/kg (50mg/kg)   Annales de l'Institut Pasteur Vol. 71, Pg. 490, 1945.
rabbit LDLo subcutaneous 50mg/kg (50mg/kg)   Annales de l'Institut Pasteur Vol. 71, Pg. 490, 1945.