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Substance Name: Fluvastatin [INN:BAN]
RN: 93957-54-1
UNII: 4L066368AS
InChIKey: FJLGEFLZQAZZCD-JUFISIKESA-N

Note

  • An indole-heptanoic acid derivative that inhibits HMG COA REDUCTASE and is used to treat HYPERCHOLESTEROLEMIA. In contrast to other statins, it does not appear to interact with other drugs that inhibit CYP3A4.

Molecular Formula

  • C24-H26-F-N-O4

Molecular Weight

  • 411.4704
 

Classification Codes

  • Anticholesteremic Agents
  • Antimetabolites
  • Enzyme Inhibitors
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Hypolipidemic Agents
  • Lipid Regulating Agents

Names and Synonyms

Name of Substance

  • Fluvastatin
  • Fluvastatin [INN:BAN]

MeSH Heading

  • Fluvastatin

Synonyms

  • Cranoc
  • Fluvastatin
  • Fluvastatina
  • Fluvastatina [INN-Spanish]
  • Fluvastatine
  • Fluvastatine [INN-French]
  • Fluvastatinum
  • Fluvastatinum [INN-Latin]
  • HSDB 8366
  • NSC 758896
  • UNII-4L066368AS
  • XU 62-320
  • XU 62320
  • XU-62320

Systematic Names

  • 6-Heptenoic acid, 7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl)- 3,5-dihydroxy-, (3R,5S,6E)-rel-
  • 6-Heptenoic acid, 7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl)- 3,5-dihydroxy-, (R*,S*-(E))-(+-)-

Registry Numbers

CAS Registry Number

  • 93957-54-1

FDA UNII

  • 4L066368AS

System Generated Number

  • 0093957541

Structure Descriptors

InChI

InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/b12-11+/t18-,19-/m0/s1

InChIKey

FJLGEFLZQAZZCD-JUFISIKESA-N

Smiles

CC(C)n1c(\C=C\[C@H](O)C[C@H](O)CC(=O)O)c(c2ccc(F)cc2)c3ccccc13

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) 4.850 (none)   EST
Atmospheric OH Rate Constant 1.97E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.