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Substance Name: Aminohippurate sodium [USP]
RN: 94-16-6
UNII: SUO3KVS1O9
InChIKey: UNZMYCAEMNVPHX-UHFFFAOYSA-M

Note

  • The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity.

Molecular Formula

  • C9-H10-N2-O3.Na

Molecular Weight

  • 216.1711
 

Classification Codes

  • Diagnostic Aid (Renal Function Determination)
  • Drug / Therapeutic Agent
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Names and Synonyms

Name of Substance

  • Aminohippurate sodium [USP]

Synonyms

  • 4-Aminohippursaeure, natriumsalz
  • Amino-hippurate-sodium
  • Aminohippurate sodium
  • Ammohippurate sodium
  • EINECS 202-309-8
  • Monosodium p-aminohippurate
  • N-(4-Aminobenzoyl)glycine monosodium salt
  • Natrium 4-aminohippurat
  • p-Aminohippurate sodium
  • p-Aminohippuric acid sodium salt
  • Paraaminohippurate Injection
  • Sodium p-aminohippurate
  • Sodium para-aminohippurate
  • UNII-SUO3KVS1O9

Systematic Names

  • Glycine, N-(4-aminobenzoyl)-, monosodium salt
  • Hippuric acid, p-amino-, monosodium salt
  • Sodium 4-aminohippurate

Registry Numbers

CAS Registry Number

  • 94-16-6

FDA UNII

  • SUO3KVS1O9

System Generated Number

  • 0000094166

Molecular Formulas

Molecular Formula

  • C9-H10-N2-O3.Na

Molecular Formula Fragments

  • C9-H10-N2-O3
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C9H10N2O3.Na/c10-7-3-1-6(2-4-7)9(14)11-5-8(12)13;/h1-4H,5,10H2,(H,11,14)(H,12,13);/q;+1/p-1

InChIKey

UNZMYCAEMNVPHX-UHFFFAOYSA-M

Smiles

c1cc(ccc1C(=O)NCC(=O)[O-])N.[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 4930mg/kg (4930mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 147, 1945.
rat LD50 intravenous 4075mg/kg (4075mg/kg)   Drugs in Japan Vol. -, Pg. 828, 1990.