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Substance Name: Pralidoxime iodide [USAN:INN:JAN]
RN: 94-63-3
UNII: 7H254VC0NT
InChIKey: QNBVYCDYFJUNLO-UHFFFAOYSA-N

Classification Codes

  • Agricultural Chemical
  • Cholinesterase Reactivator
  • Drug / Therapeutic Agent

Molecular Formula

  • C7-H9-N2-O.I

Molecular Weight

  • 264.0611
 
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Names and Synonyms

Name of Substance

  • Pralidoxime iodide
  • Pralidoxime iodide [USAN:INN:JAN]

Synonyms

  • 1-Methyl-2-aldoximinopyridinium iodide
  • 1-Methyl-2-hydroxyiminomethylpyridinium iodide
  • 2-(Hydroximinomethyl)-1-methylpyridinium iodide
  • 2-Formyl-1-methylpyridinium iodide oxime
  • 2-Formyl-N-methylpyridinium oxime iodide
  • 2-Hydroxyiminomethyl-1-methylpyridinium iodide
  • 2-PAM iodide
  • 2-Pyridinaldoxim methojodid
  • 2-Pyridinaldoxim methojodid [German]
  • 2-Pyridinaldoxime methiodide
  • 2-Pyridine aldoxime iodomethylate
  • 2-Pyridine aldoxime methiodide
  • 2-Pyridine aldoxime methyl iodide
  • 2-Pyridine aldoxymethiodide
  • 2-Pyridinecarboxaldehyde aldoxime methiodide
  • 2-Pyridylaldoxime methiodide
  • AI3-21251
  • EINECS 202-349-6
  • GS 1043
  • Iodure de pralidoxime
  • Iodure de pralidoxime [INN-French]
  • Ioduro de pralidoxima
  • Ioduro de pralidoxima [INN-Spanish]
  • N-Methylpyridine-2-aldoxime iodide
  • N-Methylpyridinium-2-aldoxime iodide
  • NSC 40164
  • NSC-7760
  • PAM (pharmaceutical)
  • Pralidossima joduro
  • Pralidossima joduro [DCIT]
  • Pralidoxime iodide
  • Pralidoxime methiodide
  • Pralidoximi iodidum
  • Pralidoximi iodidum [INN-Latin]
  • Protopam iodide
  • Pyridin-2-aldoxin
  • Pyridin-2-aldoxin [Czech]
  • Pyridine aldoxime methiodide
  • Pyridine-2-aldoxime methiodide
  • Pyridine-2-aldoxime methyl iodide
  • Pyridinium, 2-((hydroxyimino)methyl)-1-methyl-, iodide
  • Pyridinium, 2-formyl-1-methyl-, iodide, oxime
  • Pyridinium-2-aldoxime N-methyliodide
  • UNII-7H254VC0NT

Systematic Names

  • Pralidoxime iodide
  • Pyridinium, 2-((hydroxyimino)methyl)-1-methyl-, iodide
  • Pyridinium, 2-formyl-1-methyl-, iodide, oxime

Registry Numbers

CAS Registry Number

  • 94-63-3

FDA UNII

  • 7H254VC0NT

Related Registry Number

  • 6735-59-7 (Parent)

System Generated Number

  • 0000094633

Molecular Formulas

Molecular Formula

  • C7-H9-N2-O.I

Molecular Formula Fragments

  • C7-H9-N2-O
  • COMPONENT
  • I

Structure Descriptors

InChI

1S/C7H8N2O.HI/c1-9-5-3-2-4-7(9)6-8-10;/h2-6H,1H3;1H

InChIKey

QNBVYCDYFJUNLO-UHFFFAOYSA-N

Smiles

[I-].C[n+]1ccccc1\C=N\O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intramuscular 240mg/kg (240mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 5, 1964.
mouse LD50 intraperitoneal 136mg/kg (136mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Archives of Biochemistry and Biophysics. Vol. 60, Pg. 261, 1956.
mouse LD50 intravenous 145mg/kg (145mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 132, Pg. 50, 1961.
mouse LD50 oral 1500mg/kg (1500mg/kg)   Journal of Pharmaceutical Sciences. Vol. 53, Pg. 1143, 1964.
mouse LD50 subcutaneous 140mg/kg (140mg/kg)   Archives of Environmental Health. Vol. 5, Pg. 21, 1962.
rat LD50 intramuscular 249mg/kg (249mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 129, Pg. 31, 1960.
rat LD50 intraperitoneal 305mg/kg (305mg/kg)   British Journal of Pharmacology and Chemotherapy. Vol. 13, Pg. 202, 1958.
rat LD50 intravenous 178mg/kg (178mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 129, Pg. 31, 1960.