|
|
Substance Name: 2,4-D [BSI:ISO]
RN: 94-75-7
UNII: 2577AQ9262
InChIKey: OVSKIKFHRZPJSS-UHFFFAOYSA-N
Note
- An herbicide with irritant effects on the eye and the gastrointestinal system.
Molecular Formula
- C8-H6-Cl2-O3
Molecular Weight
- 221.0384
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Agricultural Chemical
- Growth Regulator / Fertilizer
- Herbicide
- Herbicides
- Human Data
- Mutation Data
- Pesticides
- Reproductive Effect
- Skin / Eye Irritant
- Tumor Data
Superlist Classification Codes
- 2007 CERCLA Priority List, Rank: 248
- 2011 CERCLA Priority List, Rank: 243
- Reportable Quantity (RQ) = 100 lb
- TWA 10 mg/m3
- TWA 10 mg/m3; Not classifiable as a human carcinogen
* denotes mobile formatted website
Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Search for this InChIKey on the Web
Names and Synonyms
Results Name
- 2,4-D [BSI:ISO]
Name of Substance
- 2,4-D
- 2,4-D [BSI:ISO]
- 2,4-Dichlorophenoxyacetic acid
MeSH Heading
- 2,4-Dichlorophenoxyacetic acid
Synonyms
- (2,4-Dichloor-fenoxy)-azijnzuur
- (2,4-Dichloor-fenoxy)-azijnzuur [Dutch]
- (2,4-Dichlor-phenoxy)-essigsaeure
- (2,4-Dichlor-phenoxy)-essigsaeure [German]
- (2,4-Dichlorophenyloxy)acetic acid
- 2,4-D
- 2,4-D acid
- 2,4-Dichlorophenoxyacetic acid
- 2,4-Dwuchlorofenoksyoctowy kwas
- 2,4-Dwuchlorofenoksyoctowy kwas [Polish]
- 2,4-PA
- 4-06-00-00908 (Beilstein Handbook Reference)
- Acetic acid, (2,4-dichlorophenoxy)-
- Acide 2,4-dichloro phenoxyacetique
- Acide 2,4-dichloro phenoxyacetique [French]
- Acido(2,4-dicloro-fenossi)-acetico
- Acido(2,4-dicloro-fenossi)-acetico [Italian]
- Acme LV 4
- Acme LV 6
- Agricorn D
- Agrotect
- AI3-08538
- Amoxone
- B-Selektonon
- Barrage
- BH 2,4-D
- BRN 1214242
- Brush-rhap
- Butoxy-D 3: 1 Liquid emulsifiable Brushkiller LV96
- Butoxy-D 3: 1 Liquid emulsifiable Brushkiller LV96 [Canada]
- Caswell No. 315
- CCRIS 949
- Chipco turf herbicide D
- Chloroxone
- Citrus fix
- Crop rider
- Croprider
- De-Pester Ded-Weed LV-2
- Debroussaillant 600
- Ded-Weed LV-69
- Deherban
- Dichlorophenoxyacetic acid
- Dicopur
- Dormon
- Dormone
- EINECS 202-361-1
- Emulsamine
- Emulsamine BK
- Emulsamine E-3
- ENT 8,538
- Envert DT
- EPA Pesticide Chemical Code 030001
- Esteron 44 weed killer
- Esteron 76 BE
- Estone
- Fernesta
- Fernimine
- Ferxone
- Foredex 75
- Green Cross Weed-No-More 80
- Hedonal
- Hedonal (the herbicide)
- Herbidal
- Hivol-44
- HSDB 202
- Ipaner
- Kwas 2,4-dwuchlorofenoksyoctowy
- Kwas 2,4-dwuchlorofenoksyoctowy [Polish]
- Kwasu 2,4-dwuchlorofenoksyoctowego
- Kwasu 2,4-dwuchlorofenoksyoctowego [Polish]
- Kyselina 2,4-dichlorfenoxyoctova
- Kyselina 2,4-dichlorfenoxyoctova [Czech]
- Lawn-keep
- Macondray
- Macrondray
- Miracle
- Mota Maskros
- Moxon
- Moxone
- Netagrone
- Netagrone 600
- NSC 2925
- Pennamine D
- Phenox
- Phenoxyacetic acid, 2,4-dichloro-
- Pielik
- Planotox
- Plantgard
- R-H Weed Rhap 20
- RCRA waste number U240
- Red Devil Dry Weed Killer
- Rhodia
- Scott's 4-XD Weed Control
- Silvaprop 1
- Superormone concentre
- Tributon
- U 46DP
- U-5043
- UNII-2577AQ9262
- Vergemaster
- Verton 2D
- Verton 38
- Vidon 638
- Visko-rhap low drift herbicides
- Visko-rhap low volatile 4l
- Weed TOX
- Weed-Ag-Bar
- Weed-B-gon
- Weed-rhap
- Weed-Rhap A-4
- Weed-Rhap B-266
- Weed-Rhap B-4
- Weed-Rhap I-3.34
- Weed-Rhap LV-4-0
- Weedatul
- Weedez Wonder BAR
- Weedone
- Weedone 100 Emulsifiable
- Weedone 100 Emulsifiable [Canada]
- Weedone LV4
- Weedtrol
Systematic Names
- 2,4-D
- 2,4-Dichlorophenoxyacetic acid
- Acetic acid, (2,4-dichlorophenoxy)-
- Acetic acid, 2-(2,4-dichlorophenoxy)-
Superlist Names
- (2,4-Dichlorophenoxy)acetic acid
- 2,4-D
- 2,4-D acid
- 2,4-D [Chlorophenoxy herbicides]
- 2,4-D, salts and esters
- 2,4-Dichlorophenoxyacetic acid
- Acetic acid, (2,4-dichlorophenoxy)-
- Acetic acid, (2,4-dichlorophenoxy)-, salts and esters
- Dichlorophenoxyacetic acid
- RCRA waste no. U240
Registry Numbers
CAS Registry Number
- 94-75-7
FDA UNII
- 2577AQ9262
Other Registry Number
- 15183-39-8
Related Registry Numbers
- 14214-89-2 (potassium salt)
- 2307-55-3 (ammonium salt)
- 2702-72-9 (hydrochloride salt)
- 3766-27-6 (lithium salt)
System Generated Number
- 0000094757
Structure Descriptors
InChI
1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)InChIKey
OVSKIKFHRZPJSS-UHFFFAOYSA-NSmiles
c1cc(c(cc1Cl)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
chicken | LD50 | oral | 541mg/kg (541mg/kg) | GASTROINTESTINAL: GASTRITIS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LIVER: FATTY LIVER DEGERATION | American Journal of Veterinary Research. Vol. 15, Pg. 622, 1954. |
dog | LD50 | oral | 100mg/kg (100mg/kg) | BEHAVIORAL: STIFFNESS BEHAVIORAL: COMA | Archives of Environmental Health. Vol. 7, Pg. 202, 1963. |
guinea pig | LD50 | intraperitoneal | 666mg/kg (666mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: COMA | Journal of Industrial Hygiene and Toxicology. Vol. 29, Pg. 85, 1947. |
guinea pig | LD50 | oral | 469mg/kg (469mg/kg) | American Journal of Veterinary Research. Vol. 15, Pg. 622, 1954. | |
hamster | LD50 | oral | 500mg/kg (500mg/kg) | Toxicology and Applied Pharmacology. Vol. 48, Pg. A192, 1979. | |
human | LDLo | oral | 80mg/kg (80mg/kg) | BEHAVIORAL: COMA GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Archives of Pathology. Vol. 94, Pg. 270, 1972. |
mammal (species unspecified) | LD50 | oral | 375mg/kg (375mg/kg) | Science. Vol. 165, Pg. 465, 1969. | |
man | LDLo | oral | 93mg/kg (93mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Pharmacological Reviews. Vol. 14, Pg. 225, 1962. |
man | TDLo | oral | 2gm/kg (2000mg/kg) | BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Archives of Toxicology. Vol. 66, Pg. 518, 1992. |
man | TDLo | oral | 5714mg/kg (5714mg/kg) | BEHAVIORAL: COMA CARDIAC: CHANGE IN RATE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Archives of Toxicology. Vol. 66, Pg. 518, 1992. |
mouse | LD50 | oral | 347mg/kg (347mg/kg) | Roczniki Panstwowego Zakladu Higieny. Vol. 31, Pg. 373, 1980. | |
mouse | LDLo | intraperitoneal | 125mg/kg (125mg/kg) | Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972. | |
rabbit | LD50 | intraperitoneal | 400mg/kg (400mg/kg) | PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: COMA | Journal of Industrial Hygiene and Toxicology. Vol. 29, Pg. 85, 1947. |
rabbit | LD50 | intravenous | 400mg/kg (400mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: COMA | Journal of Industrial Hygiene and Toxicology. Vol. 29, Pg. 85, 1947. |
rabbit | LD50 | skin | 1400mg/kg (1400mg/kg) | BEHAVIORAL: ATAXIA SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE | Quarterly Bulletin--Association of Food and Drug Officials of the United States. Vol. 16, Pg. 3, 1952. |
rabbit | LDLo | oral | 800mg/kg (800mg/kg) | Archives des Maladies Professionnelles de Medecine du Travail et de Securite Sociale. Vol. 12, Pg. 26, 1951. | |
rat | LD50 | intraperitoneal | 666mg/kg (666mg/kg) | PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: COMA | Journal of Industrial Hygiene and Toxicology. Vol. 29, Pg. 85, 1947. |
rat | LD50 | oral | 375mg/kg (375mg/kg) | Farm Chemicals Handbook. Vol. -, Pg. C174, 1991. | |
rat | LD50 | skin | 1500mg/kg (1500mg/kg) | World Review of Pest Control. Vol. 9, Pg. 119, 1970. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 140.5 | deg C | EXP | |
pKa Dissociation Constant | 2.73 | (none) | EXP | |
log P (octanol-water) | 2.81 | (none) | EXP | |
Water Solubility | 677 | mg/L | 25 | EXP |
Vapor Pressure | 8.25E-05 | mm Hg | 20 | EXP |
Henry's Law Constant | 3.54E-08 | atm-m3/mole | 25 | EST |
Atmospheric OH Rate Constant | 6.63E-12 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.