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Substance Name: Amiphenazole hydrochloride
RN: 942-31-4
InChIKey: AGSXNJJBDIOXIP-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C9-H9-N3-S.Cl-H

Molecular Weight

  • 227.718
 
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Names and Synonyms

Results Name

  • Amiphenazole hydrochloride

Synonyms

  • 2,4-Diamino 5-phenylthiazol chlorhydrate
  • 2,4-Diamino 5-phenylthiazol chlorhydrate [French]
  • 2,4-Diamino-5-phenylthiazole hydrochloride
  • 2,4-Diamino-5-phenylthiazole monohydrochloride
  • 5-Phenyl-2,4-thiazolediamine monohydrochloride
  • Amifenatsol hydrochloride
  • Amiphenazole HCl
  • Amiphenazole hydrochloride
  • Amphisol hydrochloride
  • Daptazile
  • Daptazole
  • DHA 245
  • EINECS 213-389-9
  • Fenamizol hydrochloride
  • NSC 35538
  • Phenamizole hydrochloride
  • Thiazole, 2,4-diamino-5-phenyl-, hydrochloride

Systematic Names

  • 2,4-Thiazolediamine, 5-phenyl-, monohydrochloride (9CI)
  • 5-Phenylthiazole-2,4-diamine monohydrochloride
  • Thiazole, 2,4-diamino-5-phenyl-, hydrochloride
  • Thiazole, 2,4-diamino-5-phenyl-, monohydrochloride (8CI)

Registry Numbers

CAS Registry Number

  • 942-31-4

Related Registry Number

  • 490-55-1 (Parent)

System Generated Number

  • 0000942314

Molecular Formulas

Molecular Formula

  • C9-H9-N3-S.Cl-H

Molecular Formula Fragments

  • C9-H9-N3-S
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C9H9N3S.ClH/c10-8-7(13-9(11)12-8)6-4-2-1-3-5-6;/h1-5H,10H2,(H2,11,12);1H

InChIKey

AGSXNJJBDIOXIP-UHFFFAOYSA-N

Smiles

c1(c2ccccc2)sc(N)nc1N.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 unreported 144mg/kg (144mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 110, Pg. 465, 1957.
mouse LD50 intraperitoneal 159mg/kg (159mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
Farmatsevtichnii Zhurnal Vol. 26(5), Pg. 20, 1971.
mouse LD50 oral 330mg/kg (330mg/kg)   Pharmaceutical Chemistry Journal Vol. 7, Pg. 489, 1973.
mouse LD50 subcutaneous 310mg/kg (310mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 21, Pg. 668, 1969.
rat LD50 intraperitoneal 300mg/kg (300mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 201, 1972.