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Substance Name: Yttrium Y 90 clivatuzumab tetraxetan [USAN:INN]
RN: 943976-23-6
UNII: 2L271110ED

Classification Code

  • Treatment of Pancreatic Cancer

Molecular Formula

  • C6496-H9952-N1716-O2014-S44.n(C16-H23-N4-O7-Y)

Molecular Weight

  • 489.4015
 
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Names and Synonyms

Name of Substance

  • Yttrium (90Y) clivatuzumab tetraxetan [INN]
  • Yttrium Y 90 clivatuzumab tetraxetan [USAN:INN]

Synonyms

  • (sup 90)hY-PAM4
  • hPAM4-Cide
  • hPAM4-DOTA
  • IMMU-107
  • Immunoglobulin G1, anti-(Mucin-1 (MUC-1, PEMT, Episialin, Tumor-associated mucin, EMA, H23AG, PUM or CD227)); humanized mouse monoclonal hPAM4 gamma1 heavy chain (222-215')-disulfide with humanized mouse monoclonal hPAM4 kappa light chain, dimer (228-228'':231-231'')-bisdisulfide, substituted (average of 2 to 5 substitutions) on N(sup 6) of lysyl residus by (4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclodec-1-yl)acetyl (substitutive tetraxetan), (90Y)yttrium(III) chelate
  • UNII-2L271110ED
  • Yttrium (90Y) clivatuzumab tetraxetan
  • Yttrium Y 90 clivatuzumab tetraxetan

Systematic Name

  • Immunoglobulin G1, anti-(human mucin MUC1) (human-mouse monoclonal hPAM4 heavy chain), disulfide with human-mouse monoclonal hPAM4 kappa-chain, dimer, 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid conjugate, yttrium-(sup 90)Y chelate

Registry Numbers

CAS Registry Number

  • 943976-23-6

FDA UNII

  • 2L271110ED

System Generated Number

  • 0943976236