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Substance Name: Saxagliptin [USAN:INN:BAN]
RN: 945667-22-1
UNII: 9GB927LAJW
InChIKey: AFNTWHMDBNQQPX-NHKADLRUSA-N

Note

  • Inhibits Dipeptidyl Peptidase-4.

Molecular Formula

  • C18-H25-N3-O2.H2O

Molecular Weight

  • 333.4293
 

Classification Codes

  • Dipeptidyl-Peptidase IV Inhibitors
  • Enzyme Inhibitors
  • Hormones
  • Hormones, Hormone Substitutes, and Hormone Antagonists
  • Hypoglycemic Agents
  • Incretins
  • Protease Inhibitors
  • Treatment of Type II Diabetes Mellitus and Metabolic Syndrome

Names and Synonyms

Name of Substance

  • Saxagliptin [USAN:INN:BAN]

Synonyms

  • (1S,3S,5S)-2-((2S)-Amino(3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)2- azabicyclo(3.1.0)hexane-3-carbonitrile monohydrate
  • BMS-477118-11
  • Onglyza
  • Saxagliptin
  • Saxagliptin hydrate
  • UNII-9GB927LAJW

Systematic Name

  • 2-Azabicyclo(3.1.0)hexane-3-carbonitrile, 2-((2S)-2-amino-2-(3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)-, hydrate (1:1), (1S,3S,5S)-

Registry Numbers

CAS Registry Number

  • 945667-22-1

FDA UNII

  • 9GB927LAJW

System Generated Number

  • 0945667221

Structure Descriptors

InChI

1S/C18H25N3O2.H2O/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17;/h10-15,23H,1-7,9,20H2;1H2/t10?,11?,12-,13+,14+,15-,17?,18?;/m1./s1

InChIKey

AFNTWHMDBNQQPX-NHKADLRUSA-N

Smiles

O.N[C@H](C(=O)N1[C@@H](C[C@@H]2C[C@H]12)C#N)C34CC5CC(CC(O)(C5)C3)C4