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Substance Name: Ampicillin mixture with Sulbactam
RN: 94935-63-4
InChIKey: KMEGBUCIGMEPME-LQYKFRDPSA-N
Note
- A combination of ampicillin & sulbactam used in the treatment of infectious complications & bronchopulmonary diseases; a Russian compound.
Classification Code
- Drug / Therapeutic Agent
Molecular Formula
- C16-H19-N3-O4-S.C8-H11-N-O5-S
Molecular Weight
- 581.6639
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Names and Synonyms
Results Name
- Ampicillin mixture with Sulbactam
Name of Substance
- Sulacillin
Synonyms
- Ampicillin and sulbactam
- Ampicillin sodium and sulbactam sodium
- Ampicillin-sulbactam
- Ampicillin-sulbactam mixt.
- Sulacillin
- Sulbactam-Ampicillin mixt. (1:2)
- Unasyn
Systematic Names
- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2R)-aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, (2S,5R,6R)-, mixt. with (2S,5R)-3,3-dimethyl-7-oxo-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 4,4-dioxide
- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2-alpha,5-alpha,6-beta(S*)))-, mixt. with (2S-cis)-3,3-dimethyl-7-oxo-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 4,4-dioxide
Registry Numbers
CAS Registry Number
- 94935-63-4
System Generated Number
- 0094935634
Molecular Formulas
Molecular Formula
- C16-H19-N3-O4-S.C8-H11-N-O5-S
Molecular Formula Fragments
- C16-H19-N3-O4-S
- C8-H11-N-O5-S
- COMPONENT
Structure Descriptors
InChI
InChI=1S/C16H19N3O4S.C9H12O5S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;1-9(2)7(8(11)12)6-4(10)3-5(6)15(9,13)14/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);5-7H,3H2,1-2H3,(H,11,12)/t9-,10-,11+,14-;5-,6?,7+/m11/s1InChIKey
KMEGBUCIGMEPME-LQYKFRDPSA-NSmiles
CC1(C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | > 6gm/kg (6000mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Chemotherapy Vol. 36(Suppl, |
mouse | LD50 | oral | > 6gm/kg (6000mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Chemotherapy Vol. 36(Suppl, |
mouse | LD50 | subcutaneous | > 6gm/kg (6000mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Chemotherapy Vol. 36(Suppl, |
mouse | LDLo | intravenous | 6095mg/kg (6095mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Chemotherapy Vol. 36(Suppl, |
rat | LD50 | intraperitoneal | > 6gm/kg (6000mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Chemotherapy Vol. 36(Suppl, |
rat | LD50 | intravenous | 6820mg/kg (6820mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Chemotherapy Vol. 36(Suppl, |
rat | LD50 | oral | > 6gm/kg (6000mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Chemotherapy Vol. 36(Suppl, |
rat | LD50 | subcutaneous | > 6gm/kg (6000mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Chemotherapy Vol. 36(Suppl, |