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Substance Name: Ranolazine [USAN:INN:BAN]
RN: 95635-55-5
UNII: A6IEZ5M406
InChIKey: XKLMZUWKNUAPSZ-UHFFFAOYSA-N

Note

  • An acetanilide and piperazine derivative that functions as a SODIUM CHANNEL BLOCKER and prevents the release of enzymes during MYOCARDIAL ISCHEMIA. It is used in the treatment of ANGINA PECTORIS.

Molecular Formula

  • C24-H33-N3-O4

Molecular Weight

  • 427.5417
 

Classification Codes

  • Anti-Anginal
  • Anti-Ischemic
  • Cardiovascular Agents
  • Enzyme Inhibitors
  • Membrane Transport Modulators
  • Partial Fatty Acid Oxidation (pFOX) Inhibitors
  • Sodium Channel Blockers

Names and Synonyms

Name of Substance

  • Ranolazine
  • Ranolazine [USAN:INN:BAN]

MeSH Heading

  • Ranolazine

Synonyms

  • (+-)-N-(2,6-Dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-1-piperazineacetamide
  • (+-)-Ranolazine
  • (+/-)-1-(3-(2-Methoxyphenoxy)-2-hydroxypropyl)-4-(n-(2,6-dimethylphenyl)carbamoylmethyl)piperazine
  • (+/-)-4-(2-Hydroxy-3-(o-methoxyphenoxy)propyl)-1-piperazineaceto-2',6'-xylidide
  • 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-, (+-)-
  • CVT-303
  • HSDB 7924
  • N-(2,6-Dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-1-piperazineacetamide
  • RAN D
  • Ran4
  • Ranexa
  • Ranolazine
  • RS-43285-003
  • UNII-A6IEZ5M406

Systematic Name

  • 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-

Registry Numbers

CAS Registry Number

  • 95635-55-5

FDA UNII

  • A6IEZ5M406

Other Registry Number

  • 142387-99-3

System Generated Number

  • 0095635555

Structure Descriptors

InChI

1S/C24H33N3O4/c1-18-7-6-8-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-10-5-4-9-21(22)30-3/h4-10,20,28H,11-17H2,1-3H3,(H,25,29)

InChIKey

XKLMZUWKNUAPSZ-UHFFFAOYSA-N

Smiles

COc1ccccc1OCC(O)CN2CCN(CC(=O)Nc3c(C)cccc3C)CC2