Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Cefotiam hexetil hydrochloride [JAN]
RN: 95789-30-3
UNII: 3N1X7E8CLE
InChIKey: FFSANQNELHESQJ-LWBICVDYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C27-H37-N9-O7-S3.2Cl-H

Molecular Weight

  • 768.7651
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Cefotiam hexetil hydrochloride
  • Cefotiam hexetil hydrochloride [JAN]

Synonyms

  • Cefotiam hexetil HCl
  • Cefotiam hexetil hydrochloride
  • CTM-HE
  • UNII-3N1X7E8CLE

Systematic Name

  • 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)acetyl)amino)-3-(((1-(2-(dimethylamino)ethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, 1-(((cyclohexyloxy)carbonyl)oxy)ethyl ester, dihydrochloride, (6R-(6-alpha,7-beta))-

Registry Numbers

CAS Registry Number

  • 95789-30-3

FDA UNII

  • 3N1X7E8CLE

System Generated Number

  • 0095789303

Molecular Formulas

Molecular Formula

  • C27-H37-N9-O7-S3.2Cl-H

Molecular Formula Fragments

  • C27-H37-N9-O7-S3
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C27H37N9O7S3.2ClH/c1-15(42-27(40)43-18-7-5-4-6-8-18)41-24(39)21-16(13-46-26-31-32-33-35(26)10-9-34(2)3)12-44-23-20(22(38)36(21)23)30-19(37)11-17-14-45-25(28)29-17;;/h14-15,18,20,23H,4-13H2,1-3H3,(H2,28,29)(H,30,37);2*1H/t15?,20-,23-;;/m1../s1

InChIKey

FFSANQNELHESQJ-LWBICVDYSA-N

Smiles

Cl.Cl.CC(OC(=O)OC1CCCCC1)OC(=O)C2=C(CSc3nnnn3CCN(C)C)CS[C@@H]4[C@H](NC(=O)Cc5csc(N)n5)C(=O)N24

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD unreported > 1gm/kg (1000mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 32, Pg. 1770, 1990.
mouse LD50 intraperitoneal 1150mg/kg (1150mg/kg) LIVER: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Oyo Yakuri. Pharmacometrics. Vol. 35, Pg. 179, 1988.
mouse LD50 oral > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. -, Pg. 564, 1990.
mouse LD50 subcutaneous > 2gm/kg (2000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 35, Pg. 179, 1988.
rat LD50 intraperitoneal 1470mg/kg (1470mg/kg) LIVER: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Oyo Yakuri. Pharmacometrics. Vol. 35, Pg. 179, 1988.
rat LD50 oral > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. -, Pg. 564, 1990.
rat LD50 subcutaneous > 2gm/kg (2000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 35, Pg. 179, 1988.