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Substance Name: Acetarsone [INN:NF]
RN: 97-44-9
UNII: 806529YU1N
InChIKey: ODFJOVXVLFUVNQ-UHFFFAOYSA-N
Classification Codes
- Anti-Infective Agents
- Drug / Therapeutic Agent
- Human Data
- Mutation Data
Molecular Formula
- C8-H10-As-N-O5
Molecular Weight
- 275.091
- All
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
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Names and Synonyms
Name of Substance
- Acetarsone [INN:NF]
Synonyms
- 190 F
- 3-16-00-01132 (Beilstein Handbook Reference)
- 3-Acetamido-4-hydroxy-phenylarsonic acid
- 3-Acetamido-4-hydroxybenzenearsonic acid
- 3-Acetamido-4-hydroxyphenylarsonsaeure
- 3-Acetylamino-4-hydroxyphenylarsonic acid
- Acetamino-hydroxyphenyl-arsonsaeure
- Acetarsol
- Acetarsol [INN:BAN]
- Acetarsolo
- Acetarsolo [DCIT]
- Acetarsolum
- Acetarsolum [INN-Latin]
- Acetarsone
- Acetphenarsine
- AI3-16141
- Amarsan
- Amoebal
- Arsaphen
- Arsonine
- BRN 2941984
- Chrlich 594
- Devegan
- Disparicida
- Dynarsan
- Ehrlich 594
- EINECS 202-582-3
- F 190
- Fourneau 190
- Ginarsol
- Goyl
- Gynoplix
- Kharophen
- Kubarsol
- Limarsol
- Malagride
- Mexyl
- Monargan
- N-Acetyl-4-hydroxy-m-arsanilic acid
- Nilacid
- NSC 13160
- Oralcid
- Orarsan
- Osarsal
- Osarsol
- Osarsole
- Osarsolum
- Osvarsan
- Osvarson
- Pallicid
- Paroxyl
- Sanogyl
- Spirocid
- Spirozid
- Stovarsal
- Stovarsol
- Stovarsolan
- SVC
- UNII-806529YU1N
- Vagisept
- Vagoflor
Systematic Names
- Acetarsol
- Arsonic acid, (3-(acetylamino)-4-hydroxyphenyl)-
- m-Arsanilic acid, N-acetyl-4-hydroxy-
- N-Acetyl-4-hydroxy-m-arsanilic acid
Registry Numbers
CAS Registry Number
- 97-44-9
FDA UNII
- 806529YU1N
Related Registry Numbers
- 55588-51-7 (unspecified hydrochloride salt)
- 5892-48-8 (mono-hydrochloride salt)
- 64046-96-4 (calcium salt)
- 64046-96-4 (unspecified calcium salt)
System Generated Number
- 0000097449
Structure Descriptors
InChI
InChI=1S/C8H10AsNO5/c1-5(11)10-7-4-6(9(13,14)15)2-3-8(7)12/h2-4,12H,1H3,(H,10,11)(H2,13,14,15)InChIKey
ODFJOVXVLFUVNQ-UHFFFAOYSA-NSmiles
CC(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LDLo | oral | 150mg/kg (150mg/kg) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 27, Pg. 267, 1930. | |
cat | LDLo | oral | 150mg/kg (150mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE | Proceedings of the Society for Experimental Biology and Medicine. Vol. 27, Pg. 267, 1930. |
man | TDLo | oral | 89mg/kg/9D (89mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES ENDOCRINE: OTHER CHANGES SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | American Journal of the Medical Sciences. Vol. 174, Pg. 819, 1927. |
mouse | LD50 | intravenous | 180mg/kg (180mg/kg) | U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03309, | |
mouse | LD50 | oral | 4mg/kg (4mg/kg) | Compilation of LD50 Values of New Drugs. | |
rabbit | LDLo | intravenous | 120mg/kg (120mg/kg) | Archives of Dermatology and Syphilology. Vol. 25, Pg. 799, 1932. | |
rabbit | LDLo | oral | 125mg/kg (125mg/kg) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 27, Pg. 267, 1930. | |
rabbit | LDLo | oral | 125mg/kg (125mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE | Proceedings of the Society for Experimental Biology and Medicine. Vol. 27, Pg. 267, 1930. |
rat | LDLo | intravenous | 300mg/kg (300mg/kg) | Archives of Dermatology and Syphilology. Vol. 25, Pg. 799, 1932. | |
rat | LDLo | oral | 1200mg/kg (1200mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 3, Pg. 44, 1948. | |
women | LDLo | intravaginal | 155mg/kg/2D-I (155mg/kg) | BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" GASTROINTESTINAL: NAUSEA OR VOMITING | British Medical Journal. Vol. 1, Pg. 1282, 1961. |
women | LDLo | intravaginal | 1576mg/kg/2D- (1576mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED | British Medical Journal. Vol. 2, Pg. 242, 1960. |
women | TDLo | oral | 86mg/kg/8D (86mg/kg) | SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | American Journal of the Medical Sciences. Vol. 174, Pg. 819, 1927. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
log P (octanol-water) | -1.340 | (none) | EST | |
Atmospheric OH Rate Constant | 1.80E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.