Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Mosapramine hydrochloride [JAN]
RN: 98043-60-8
UNII: 6M1W6HZL1X
InChIKey: CVCDAZZJQWLXHM-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C28-H35-Cl-N4-O.2Cl-H

Molecular Weight

  • 551.9863
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Mosapramine dihydrochloride
  • Mosapramine hydrochloride [JAN]
  • Y 516

Synonyms

  • Clospipramine
  • Cremin
  • Mosapramine hydrochloride
  • UNII-6M1W6HZL1X
  • Y 516
  • Y-516

Systematic Names

  • Spiro(imidazo(1,2-a)pyridine-3(2H),4'-piperidin)-2-one, 1'-(3-(3-chloro-10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)hexahydro-, dihydrochloride
  • Spiro(imidazo(1,2-a)pyridine-3(2H),4'-piperidin)-2-one, hexahydro-1'-(3-(3-chloro-10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)-, dihydrochloride, (+-)-

Registry Numbers

CAS Registry Number

  • 98043-60-8

FDA UNII

  • 6M1W6HZL1X

System Generated Number

  • 0098043608

Molecular Formulas

Molecular Formula

  • C28-H35-Cl-N4-O.2Cl-H

Molecular Formula Fragments

  • C28-H35-Cl-N4-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C28H35ClN4O.2ClH/c29-23-12-11-22-10-9-21-6-1-2-7-24(21)32(25(22)20-23)16-5-15-31-18-13-28(14-19-31)27(34)30-26-8-3-4-17-33(26)28;;/h1-2,6-7,11-12,20,26H,3-5,8-10,13-19H2,(H,30,34);2*1H

InChIKey

CVCDAZZJQWLXHM-UHFFFAOYSA-N

Smiles

c1ccc2c(c1)CCc3ccc(cc3N2CCCN4CCC5(CC4)C(=O)NC6N5CCCC6)Cl.Cl.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 1gm/kg (1000mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 33, Pg. 791, 1991.
mouse LD50 intraperitoneal 74mg/kg (74mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 37, Pg. 529, 1989.
mouse LD50 intraperitoneal 74mg/kg (74mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Oyo Yakuri. Pharmacometrics. Vol. 37, Pg. 529, 1989.
mouse LD50 oral 1008mg/kg (1008mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 37, Pg. 529, 1989.
mouse LD50 oral 1008mg/kg (1008mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Oyo Yakuri. Pharmacometrics. Vol. 37, Pg. 529, 1989.
mouse LD50 subcutaneous 1147mg/kg (1147mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 37, Pg. 529, 1989.
mouse LD50 subcutaneous 1147mg/kg (1147mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Oyo Yakuri. Pharmacometrics. Vol. 37, Pg. 529, 1989.
rat LD50 intraperitoneal 201mg/kg (201mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 37, Pg. 529, 1989.
rat LD50 intraperitoneal 201mg/kg (201mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Oyo Yakuri. Pharmacometrics. Vol. 37, Pg. 529, 1989.
rat LD50 oral 4912mg/kg (4912mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 37, Pg. 529, 1989.
rat LD50 oral 4912mg/kg (4912mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Oyo Yakuri. Pharmacometrics. Vol. 37, Pg. 529, 1989.
rat LD50 subcutaneous > 12gm/kg (12000mg/kg) BEHAVIORAL: TREMOR

SKIN AND APPENDAGES (SKIN): HAIR: OTHER

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Oyo Yakuri. Pharmacometrics. Vol. 37, Pg. 529, 1989.