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Substance Name: N,N-Dimethyl-p-benzenediamine
RN: 99-98-9
UNII: 7GZH2FMK7X
InChIKey: BZORFPDSXLZWJF-UHFFFAOYSA-N

Molecular Formula

  • C8-H12-N2

Molecular Weight

  • 136.1968
 

Classification Codes

Classification Codes

  • Agricultural Chemical
  • Coloring Agents
  • Experimental Pesticide
  • Fluorescent Dyes
  • Human Data
  • Indicators and Reagents
  • Luminescent Agents
  • Mutation Data
  • Unspecified / Unclassified Pesticide

Superlist Classification Code

  • Threshold Planning Quantity (TPQ) = 10/10000 lb
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Names and Synonyms

Name of Substance

  • 1,4-Benzenediamine, N,N-dimethyl-
  • CI 76075
  • Dimethyl-4-phenylenediamine
  • Dimethyl-p-phenylenediamine
  • N,N-Dimethyl-1,4-benzenediamine
  • N,N-Dimethyl-p-benzenediamine
  • N,N-Dimethyl-p-phenylenediamine

Synonyms

  • 1,4-Benzenediamine, N,N-dimethyl-
  • 4-(Dimethylamino)aniline
  • 4-(Dimethylamino)benzenamine
  • 4-(Dimethylamino)phenylamine
  • 4-Amino-N,N-dimethylaniline
  • AI3-52360
  • C.I. 76075
  • CCRIS 6024
  • CI 76075
  • Dimethyl-p-phenylenediamine
  • Dimethyl-p-phenylenediamine (VAN)
  • Dimethyl-para-phenylenediamine
  • DMPD
  • EINECS 202-807-5
  • HSDB 5330
  • N,N'-Dimethyl-P-phenylenediamine
  • N,N-Dimethyl-1,4-benzenediamine
  • N,N-Dimethyl-1,4-phenylenediamine
  • N,N-Dimethyl-p-benzenediamine
  • N,N-Dimethyl-p-fenylendiamin
  • N,N-Dimethyl-p-fenylendiamin [Czech]
  • N,N-Dimethyl-p-phenylenediamine
  • NSC 1493
  • p-(Dimethylamino)aniline
  • p-Amino-N,N-dimethylaniline
  • p-Aminodimethylaniline
  • p-Dimethylaminophenylamine
  • p-Phenylenediamine, N,N-dimethyl-
  • UNII-7GZH2FMK7X

Systematic Names

  • 1,4-Benzenediamine, N,N-dimethyl-
  • 1,4-Benzenediamine, N1,N1-dimethyl-
  • 4-Amino-N,N-dimethylaniline
  • N,N-Dimethyl-p-phenylenediamine
  • p-Phenylenediamine, N,N-dimethyl-

Superlist Name

  • Dimethyl-p-phenylenediamine

Registry Numbers

CAS Registry Number

  • 99-98-9

FDA UNII

  • 7GZH2FMK7X

Related Registry Numbers

  • 13806-04-7 (unspecified hydrochloride)
  • 2052-46-2 (mono-hydrochloride)
  • 24631-29-6 (oxalate[1:1])
  • 536-46-9 (di-hydrochloride)
  • 536-47-0 (sulfate[1:1])
  • 60160-75-0 (sulfate[2:1])
  • 6219-73-4 (unspecified sulfate)
  • 62778-12-5 (oxalate[2:1])

System Generated Number

  • 0000099989

Structure Descriptors

InChI

1S/C8H12N2/c1-10(2)8-5-3-7(9)4-6-8/h3-6H,9H2,1-2H3

InChIKey

BZORFPDSXLZWJF-UHFFFAOYSA-N

Smiles

CN(C)c1ccc(cc1)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo oral 20mg/kg (20mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
dog LDLo intraperitoneal 10mg/kg (10mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 262, 1949.
dog LDLo intravenous 51mg/kg (51mg/kg)   Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
dog LDLo skin 84mg/kg (84mg/kg)   Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
guinea pig LCLo inhalation 240ppb (0.24ppm) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
guinea pig LD50 intraperitoneal 45mg/kg (45mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 262, 1949.
guinea pig LD50 skin 500uL/kg (0.5mL/kg)   National Technical Information Service. Vol. OTS0555326,
guinea pig LDLo subcutaneous 100mg/kg (100mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
human TDLo skin 14ug/kg (0.014mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER TOPICAL EXPOSURE"

BLOOD: HEMORRHAGE

SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
mouse LD50 intraperitoneal 25mg/kg (25mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 262, 1949.
mouse LD50 oral 30mg/kg (30mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: TREMOR
National Technical Information Service. Vol. OTS0555326,
rabbit LCLo inhalation 500ppb (0.5ppm) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
rabbit LD50 intraperitoneal 100mg/kg (100mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 262, 1949.
rabbit LDLo oral 150mg/kg (150mg/kg) BEHAVIORAL: COMA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
rabbit LDLo skin 60mg/kg (60mg/kg) BEHAVIORAL: GENERAL ANESTHETIC

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
rabbit LDLo subcutaneous 60mg/kg (60mg/kg) BEHAVIORAL: COMA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
rat LD50 intraperitoneal 21mg/kg (21mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 262, 1949.
rat LD50 oral 50mg/kg (50mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: TREMOR
National Technical Information Service. Vol. OTS0555326,
rat LDLo subcutaneous 50mg/kg (50mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: COMA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 53 deg C   EXP
Boiling Point 263 deg C   EXP
pKa Dissociation Constant 6.59 (none) 25 EXP
log P (octanol-water) 1.250 (none)   EST
Water Solubility 8680 mg/L 25 EST
Vapor Pressure 7.91E-03 mm Hg 25 EST
Henry's Law Constant 3.03E-08 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.03E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.