|
|
|
Substance Name: Orotic acid [INN:BAN:JAN]
RN: 65-86-1
UNII: 61H4T033E5
InChIKey: PXQPEWDEAKTCGB-UHFFFAOYSA-N
Note
- An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
Molecular Formula
- C5-H4-N2-O4
Molecular Weight
- 156.0966
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Drug / Therapeutic Agent
- Mutation Data
* denotes mobile formatted website
Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Search for this InChIKey on the Web
Names and Synonyms
Name of Substance
- Orotic acid
- Orotic acid [INN:BAN:JAN]
MeSH Heading
- Orotic acid
Synonyms
- 1,2,3,4-Tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid
- 1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidecarboxylic acid
- 1,2,3,6-Tetrahydro-2,6-dioxopyrimidin-4-carbonsaeure
- 2,6-Dihydroxy-4-pyrimidinecarboxylic acid
- 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-
- 6-Carboxyuracil
- 6-Uracilcarboxylic acid
- Acide orotique
- Acide orotique [French]
- Acide orotique [INN-French]
- Acido orotico
- Acido orotico [INN-Spanish]
- Acido orotico [Spanish]
- Acidum oroticum
- Acidum oroticum [INN-Latin]
- Acidum oroticum [Latin]
- AI3-25478
- Animal galactose factor
- CCRIS 3929
- EINECS 200-619-8
- HSDB 6377
- Molkensaeure
- NSC 9791
- Orodin
- Oropur
- Orotic acid
- Orotonin
- Orotonsan
- Orotsaeure
- Orotsaeure [German]
- Oroturic
- Orotyl
- UNII-61H4T033E5
- Uracil-6-carbosaeure
- Vitamin B13
- Whey factor
Systematic Names
- 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-
- Orotic acid
- Orotic acid (VAN) (8CI)
Superlist Name
- Orotic acid
Registry Numbers
CAS Registry Number
- 65-86-1
FDA UNII
- 61H4T033E5
Other Registry Numbers
- 58915-47-2
- 6784-70-9
System Generated Number
- 0000065861
Structure Descriptors
InChI
InChI=1S/C5H4N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h1H,(H,9,10)(H2,6,7,8,11)InChIKey
PXQPEWDEAKTCGB-UHFFFAOYSA-NSmiles
OC(=O)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 841mg/kg (841mg/kg) | Drugs in Japan Vol. 6, Pg. 165, 1982. | |
| mouse | LD50 | intravenous | 770mg/kg (770mg/kg) | Drugs in Japan Vol. 6, Pg. 165, 1982. | |
| mouse | LD50 | oral | 2gm/kg (2000mg/kg) | Drugs in Japan Vol. 6, Pg. 165, 1982. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 345.5 | deg C | EXP | |
| log P (octanol-water) | -0.83 | (none) | EXP | |
| Water Solubility | 1820 | mg/L | 18 | EXP |
| Vapor Pressure | 1.03E-08 | mm Hg | 25 | EST |
| Henry's Law Constant | 8.10E-15 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 8.91E-12 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.