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Substance Name: Polysorbate 20 [USAN:INN:BAN:NF]
RN: 9005-64-5
Note
- Sorbitan mono-9-octadecanoate poly(oxy-1,2-ethanediyl) derivatives; complex mixtures of polyoxyethylene ethers used as emulsifiers or dispersing agents in pharmaceuticals.
Molecular Formulas
- C58-H114-O26
- Unspecified
Molecular Weight
- 520.6552
Classification Codes
- Drug / Therapeutic Agent
- Pharmaceutic Aid (Surfactant)
- Reproductive Effect
- Skin / Eye Irritant
- TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)
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Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Names and Synonyms
Name of Substance
- PEG-10 Sorbitan laurate
- PEG-40 Sorbitan laurate
- PEG-44 Sorbitan laurate
- PEG-75 Sorbitan laurate
- PEG-80 Sorbitan laurate
- Polyethylene glycol (44) sorbitan monolaurate
- Polyethylene glycol (80) sorbitan monolaurate
- Polyethylene glycol 2000 sorbitan laurate
- Polyethylene glycol 4000 sorbitan monolaurate
- Polyethylene glycol 500 sorbitan monolaurate
- Polyoxyethylene (10) sorbitan monolaurate
- Polyoxyethylene (20) sorbitan monolaurate
- Polyoxyethylene (4) sorbitan monolaurate
- Polyoxyethylene (40) sorbitan laurate
- Polyoxyethylene (44) sorbitan monolaurate
- Polyoxyethylene (75) sorbitan monolaurate
- Polyoxyethylene (80) sorbitan monolaurate
- Polysorbate 20
- Polysorbate 20 [USAN:INN:BAN:NF]
- Polysorbate 21
- Sorbimacrogol laurate 300
- Sorbitan, monododecanoate, poly(oxy-1,2-ethanediyl) derivs.
Synonyms
- Armotan pml-20
- Capmul
- CCRIS 699
- Dxewmulse poe-sml
- EC 500-018-3
- Emsorb 6915
- FEMA No. 2915
- Glycosperse L-20
- Glycosperse L-20X
- Hodag psml-20
- HSDB 7824
- Liposorb L-20
- Peg sorbitan laurate
- Peg-20 sorbitan laurate
- Poe 20 sorbitan monolaurate
- Polyoxyethylene 20 sorbitan monolaurate
- Polyoxyethylene sorbitan monolaurate
- Polyoxyethylene(4)sorbitan monolaurate
- Polysorbate 20
- Polysorbate 21
- Protasorb L-20
- PSML
- Sorbimacrogol laurate 300
- Sorbitan, monododecanoate, poly(oxy-1,2-ethanediyl) derivs.
- Sorbitan, monododecanote, poly(oxy-1,2-ethanediyl) derivatives
- Sorbitan, monolaurate, polyoxyethylene derivs.
- Tween 20
- Tween 21
- UNII-239B50Y732
- UNII-31JQ3WOL8T
- UNII-4Z93U4C2WN
- UNII-59IO08SBZU
- UNII-7T1F30V5YH
- UNII-I42X3Q0FMF
Systematic Names
- Polyoxyethylene sorbitan monolaurate
- Polysorbate 20
- Sorbitan monolaurate, ethoxylated
- Sorbitan, monododecanoate, poly(oxy-1,2-ethanediyl) derivs.
Superlist Names
- Polyoxyethylene sorbitan monolaurate
- Polysorbate 20
Registry Numbers
CAS Registry Number
- 9005-64-5
FDA UNIIs
- 239B50Y732
- 31JQ3WOL8T
- 4Z93U4C2WN
- 59IO08SBZU
- 7T1F30V5YH
- I42X3Q0FMF
Other Registry Numbers
- 118955-39-8
- 122304-31-8
- 1242241-45-7
- 129428-64-4
- 1341-06-6
- 1646144-25-3
- 194879-92-0
- 1994335-01-1
- 2488693-42-9
- 37310-96-6
- 54174-54-8
- 60318-54-9
- 62229-28-1
- 8036-82-6
- 851015-03-7
- 861842-35-5
- 9011-30-7
- 9015-57-0
- 93037-36-6
System Generated Number
- 0009005645
Structure Descriptors
Smiles
Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| hamster | LD50 | oral | 18mL/kg (18mL/kg) | Food Research. Vol. 21, Pg. 348, 1956. | |
| mouse | LD50 | intraperitoneal | 2640mg/kg (2640mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976. | |
| mouse | LD50 | intravenous | 1420mg/kg (1420mg/kg) | Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 316, 1970. | |
| mouse | LD50 | oral | > 33gm/kg (33000mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976. | |
| rat | LD50 | intraperitoneal | 3850mg/kg (3850mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976. | |
| rat | LD50 | intravenous | 770mg/kg (770mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976. | |
| rat | LD50 | oral | 36700uL/kg (36.7mL/kg) | Food Research. Vol. 21, Pg. 348, 1956. |