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Substance Name: Memantine [INN:BAN]
RN: 19982-08-2
UNII: W8O17SJF3T
InChIKey: BUGYDGFZZOZRHP-UHFFFAOYSA-N
Note
- AMANTADINE derivative that has some dopaminergic effects. It has been proposed as an antiparkinson agent.
Molecular Formula
- C12-H21-N
Molecular Weight
- 179.305
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- Classifications
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- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Physical Properties
Classification Codes
- Anti-Dyskinesia Agents
- Antiparkinson Agents
- Antiviral (COVID-19)
- Central Nervous System Agents
- Dopamine Agents
- Excitatory Amino Acid Agents
- Excitatory Amino Acid Antagonists
- N-Methyl-D-Asparate (NMDA) Antagonist
- Neurotransmitter Agents
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Links to Resources
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Names and Synonyms
Name of Substance
- Memantine
- Memantine [INN:BAN]
MeSH Heading
- Memantine
Synonyms
- 1,3-Dimethyl-5-adamantanamine
- 1-Amino-3,5-dimethyladamantane
- 3,5-Dimethyl-1-adamantylamine
- 3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
- Alzantin
- D 145
- DMAA [Antiparkinson Agent]
- DRG 0267
- Ebixa
- HSDB 7327
- Memantina
- Memantina [INN-Spanish]
- Memantine
- Memantinum
- Memantinum [INN-Latin]
- NSC 757843
- UNII-W8O17SJF3T
Systematic Names
- 3,5-Dimethyl-1-adamantanamine
- Tricyclo(3.3.1.1(3,7))decan-1-amine, 3,5-dimethyl-
Registry Numbers
CAS Registry Number
- 19982-08-2
FDA UNII
- W8O17SJF3T
Other Registry Number
- 51052-62-1
Related Registry Number
- 41100-52-1 (Hydrochloride)
System Generated Number
- 0019982082
Structure Descriptors
InChI
InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3InChIKey
BUGYDGFZZOZRHP-UHFFFAOYSA-NSmiles
CC12CC3CC(C)Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 258 | deg C | EXP | |
| log P (octanol-water) | 3.28 | (none) | EXP | |
| Water Solubility | 894 | mg/L | 25 | EST |
| Vapor Pressure | 0.036 | mm Hg | 25 | EST |
| Henry's Law Constant | 1.47E-05 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 3.34E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.