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Substance Name: Mustargen regimen with Oncovin, Procarbazine and Prednisone
ID: C014553000
InChIKey: YYVYQPURTWSOJG-SNSGICDFSA-N

Note

  • Chemotherapy protocol consisting of ... /four/ cpds; used in treating Hodgkins disease; MOP is combination without prednisone.

    NCI: A chemotherapy regimen consisting of mechlorethamine, vincristine (Oncovin), procarbazine and prednisone, used alone or in combination with radiation therapy for the treatment of stage I-IV Hodgkin lymphoma. Due to the increased risk of gonadal toxicity, this regimen has been widely replaced by the ABVD regimen. (NCI Thesaurus)

Molecular Weight

  • 1560.7548
 
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Names and Synonyms

Results Name

  • Mustargen regimen with Oncovin, Procarbazine and Prednisone

Name of Substance

  • MOPP regimen

Synonyms

  • MOPP
  • MOPP protocol
  • MOPP regimen
  • Mustargen / Oncovin / Procarbazine / Prednisone regimen
  • Mustargen-Oncovin-Procarbazine-Prednisone regimen

Registry Number

  • C014553000

Structure Descriptors

InChI

1S/C46H56N4O10.C21H26O5.C12H19N3O.C5H11Cl2N/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(16-20-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-15-14-31-34(35(32)57-4)50(26-51)38-44(31)18-21-49-19-11-17-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6;1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19;1-9(2)15-12(16)11-6-4-10(5-7-11)8-14-13-3;1-8(4-2-6)5-3-7/h9-15,17,26,28,37-39,47,55-56H,7-8,16,18-25H2,1-6H3;5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3;4-7,9,13-14H,8H2,1-3H3,(H,15,16);2-5H2,1H3/t28-,37-,38+,39+,42-,43+,44+,45-,46-;14-,15-,18+,19-,20-,21-;;/m00../s1

InChIKey

YYVYQPURTWSOJG-SNSGICDFSA-N

Smiles

ClCCN(CCCl)C.N12[C@H]3[C@@](C=CC1)([C@H]([C@]([C@H]1[C@@]3(c3c(N1C=O)c(c(cc3)[C@@]1(C3=[C@@H](c4c(N3)cccc4)CCN3C[C@@H](C[C@@](C3)(O)CC)C1)C(=O)OC)OC)CC2)(O)C(=O)OC)OC(=O)C)CC.c1(C(=O)NC(C)C)ccc(CNNC)cc1.[C@@H]12CC[C@]([C@]1(CC(=O)[C@@H]1[C@@]3(C(=CC(=O)C=C3)CC[C@@H]21)C)C)(O)C(=O)CO