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Substance Name: Fluorouracil regimen with leucovorin calcium and oxaliplatin
ID: C410216000
InChIKey: CELHMTIXXCNWRR-YYFJYKOTSA-L

Note

  • Chemotherapy protocol consisting of oxaliplatin, 5-fluorouracil, & folinic acid (Folfox) for the treatment of metastatic renal cell carcinoma.

    NCI: One of several chemotherapy regimens that include leucovorin calcium (calcium folinate), 5-fluorouracil and oxaliplatin and which may be used in the treatment of advanced-stage and metastatic colorectal cancer. FOLFOX regimens differ in agent dosing and administration schedule and include FOLFOX 4, FOLFOX 6, modified FOLFOX 6 (mFOLFOX 6) and FOLFOX 7. (NCI Thesaurus)

Molecular Weight

  • 996.818
 
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Names and Synonyms

Results Name

  • Fluorouracil regimen with leucovorin calcium and oxaliplatin

Name of Substance

  • FOLFOX protocol

Synonyms

  • Fluorouracil regimen with leucovorin calcium and oxaliplatin
  • FOLFOX
  • FOLFOX regimen
  • FOLFOX-4
  • FOLFOX-4 protocol
  • FOLFOX-6
  • FOLFOX-6 protocol
  • FOLFOX-7
  • FOLFOX-7 protocol

Registry Numbers

ID Number

  • C410216000

System Generated Number

  • C410216000

Structure Descriptors

InChI

1S/C20H23N7O7.C8H14.C4H3FN2O2.C2H2O4.Pt/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;1-7-5-3-4-6-8(7)2;5-2-1-6-4(9)7-3(2)8;3-1(4)2(5)6;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);7-8H,1-6H2;1H,(H2,6,7,8,9);(H,3,4)(H,5,6);/q;;;;+2/p-2/t12?,13-;7-,8-;;;/m01.../s1

InChIKey

CELHMTIXXCNWRR-YYFJYKOTSA-L

Smiles

c1cc(ccc1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCC2CNc3c(c(=O)nc([nH]3)N)N2C=O.c1c(c(=O)[nH]c(=O)[nH]1)F.C1CC[C@H]2C[Pt]3(C[C@@H]2C1)OC(=O)C(=O)O3