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Substance Name: Toxin, clostridium tetani
ID: XW58142000

Note

  • Protein synthesized by CLOSTRIDIUM TETANI as a single chain of ~150 kDa with 35% sequence identity to BOTULINUM TOXIN that is cleaved to a light and a heavy chain that are linked by a single disulfide bond. Tetanolysin is the hemolytic and tetanospasmin is the neurotoxic principle. The toxin causes disruption of the inhibitory mechanisms of the CNS, thus permitting uncontrolled nervous activity, leading to fatal CONVULSIONS.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Natural Product
  • Neurotoxins
  • Noxae
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Links to Resources

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Other Resources (Internet Locators)

Names and Synonyms

MeSH Heading

  • Tetanus Toxin

Synonym

  • Clostridium tetani toxin

Systematic Name

  • Toxin, clostridium tetani

Registry Numbers

ID Number

  • NIOSH/XW5814200

System Generated Number

  • XW58142000