Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Nafenopin [USAN:INN:BAN]
RN: 3771-19-5
UNII: 093W78U96W
InChIKey: XJGBDJOMWKAZJS-UHFFFAOYSA-N

Note

  • A peroxisome proliferator that is used experimentally to promote liver tumors. It has been used as an antihyperlipoproteinemic agent.

Molecular Formula

  • C20-H22-O3

Molecular Weight

  • 310.3908
 

Classification Codes

Classification Codes

  • Antihyperlipoproteinemic
  • Antimetabolites
  • Carcinogens
  • Drug / Therapeutic Agent
  • Hypolipidemic Agents
  • Lipid Regulating Agents
  • Mutation Data
  • Noxae
  • Peroxisome Proliferators
  • Tumor Data

Superlist Classification Code

  • Overall Carcinogenic Evaluation: Group 2B
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Nafenopin
  • Nafenopin [USAN:INN:BAN]

MeSH Heading

  • Nafenopin

Synonyms

  • 2-Methyl-2-(4-(1,2,3,4-tetrahydro-1-naphthalenyl)phenoxy)propanoic acid
  • 2-Methyl-2-(4-(1,2,3,4-tetrahydro-1-naphthyl)phenoxy)propanoic acid
  • 2-Methyl-2-(p-(1,2,3,4-tetrahydro-1-naphthyl)phenoxy)propionic acid
  • alpha-Methyl-alpha-(p-1,2,3,4-tetrahydronaphth-1-ylphenoxy)propionic acid
  • BRN 2005820
  • C 13437 SU
  • CCRIS 421
  • CH 13-437
  • CH 13437
  • Ciba 13437 SU
  • Melipan
  • Nafenoic acid
  • Nafenopin
  • Nafenopine
  • Nafenopine [INN-French]
  • Nafenopino
  • Nafenopino [INN-Spanish]
  • Nafenopinum
  • Nafenopinum [INN-Latin]
  • Propanoic acid, 2-methyl-2-(4-(1,2,3,4-tetrahydro-1-naphthalenyl)phenoxy)-
  • SU 13437
  • SU-13437
  • TPIA
  • UNII-093W78U96W

Systematic Names

  • Nafenopin
  • Propanoic acid, 2-methyl-2-(4-(1,2,3,4-tetrahydro-1-naphthalenyl)phenoxy)-
  • Propionic acid, 2-methyl-2-(p-(1,2,3,4-tetrahydro-1-naphthyl)phenoxy)-

Superlist Names

  • Nafenopin
  • Propanoic acid, 2-methyl-2-(4-(1,2,3,4-tetrahydro-1-naphthalenyl)phenoxy)-

Registry Numbers

CAS Registry Number

  • 3771-19-5

FDA UNII

  • 093W78U96W

System Generated Number

  • 0003771195

Structure Descriptors

InChI

1S/C20H22O3/c1-20(2,19(21)22)23-16-12-10-15(11-13-16)18-9-5-7-14-6-3-4-8-17(14)18/h3-4,6,8,10-13,18H,5,7,9H2,1-2H3,(H,21,22)

InChIKey

XJGBDJOMWKAZJS-UHFFFAOYSA-N

Smiles

C1(c2c(CCC1)cccc2)c1ccc(cc1)OC(C(=O)O)(C)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 oral 900mg/kg (900mg/kg)   Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.