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Substance Name: Ether [USP:JAN]
RN: 60-29-7
UNII: 0F5N573A2Y
InChIKey: RTZKZFJDLAIYFH-UHFFFAOYSA-N
Note
- A mobile, very volatile, highly flammable liquid used as an inhalation anesthetic and as a solvent for waxes, fats, oils, perfumes, alkaloids, and gums. It is mildly irritating to skin and mucous membranes.
Molecular Formula
- C4-H10-O
Molecular Weight
- 74.122
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Anesthetic (Inhalation)
- Anesthetics
- Anesthetics, General
- Anesthetics, Inhalation
- Central Nervous System Agents
- Central Nervous System Depressants
- Drug / Therapeutic Agent
- Human Data
- Mutation Data
- Skin / Eye Irritant
- Solvents
- Tumor Data
Superlist Classification Codes
- 2007 CERCLA Priority List, Rank: 255
- 2011 CERCLA Priority List, Rank: 252
- Reportable Quantity (RQ) = 100 lb
- TWA (400 ppm); STEL (500 ppm)
- TWA 400 ppm (1200 mg/m3)
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Names and Synonyms
Name of Substance
- Diethyl ether
- Ether [USP:JAN]
- Ether, ethyl
MeSH Heading
- Ether
Synonyms
- 1,1'-Oxybisethane
- 3-Oxapentane
- Aether
- AI3-24233
- Anaesthetic ether
- Anesthesia ether
- Anesthetic ether
- Anhydrous ether
- Diaethylaether
- Diaethylaether [German]
- Diethyl oxide
- Dwuetylowy eter
- Dwuetylowy eter [Polish]
- EC 200-467-2
- EINECS 200-467-2
- Etere etilico
- Etere etilico [Italian]
- Ethane, 1,1'-oxybis-
- Ether
- Ether anhydrous
- Ether ethylique
- Ether ethylique [French]
- Ether, anhydrous
- Ether, ethyl
- Ethoxyethane
- Ethyl ether
- Ethyl ether, tech.
- Ethyl oxide
- HSDB 70
- NSC 100036
- Oxyde d'ethyle
- Oxyde d'ethyle [French]
- Pronarcol
- RCRA waste number U117
- Solvent ether
- UNII-0F5N573A2Y
Systematic Names
- Diethyl ether
- Ethane, 1,1'-oxybis-
- Ethyl ether
Superlist Names
- Diethyl ether
- Diethyl ether or ethyl ether
- Diethyl ether or ethyl ether [UN1155] [Flammable liquid]
- Diethyl ether [Anaesthetics, volatile]
- Ethane, 1,1'-oxybis-
- Ether
- Ethyl ether
- RCRA waste no. U117
- UN1155
Registry Numbers
CAS Registry Number
- 60-29-7
FDA UNII
- 0F5N573A2Y
Other Registry Numbers
- 1480389-44-3
- 74446-43-8
- 7578-39-4
- 927820-24-4
System Generated Number
- 0000060297
Structure Descriptors
InChI
InChI=1S/C4H10O/c1-3-5-4-2/h3-4H2,1-2H3InChIKey
RTZKZFJDLAIYFH-UHFFFAOYSA-NSmiles
CCOCCToxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LCLo | inhalation | 76000ppm (76000ppm) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1294, 1935. | |
frog | LDLo | subcutaneous | 24gm/kg (24000mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1295, 1935. | |
guinea pig | LDLo | intraperitoneal | 2gm/kg (2000mg/kg) | American Industrial Hygiene Association Journal. Vol. 35, Pg. 21, 1974. | |
human | TCLo | inhalation | 200ppm (200ppm) | SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION | Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 282, 1943. |
man | LDLo | oral | 260mg/kg (260mg/kg) | "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970. | |
mouse | LC50 | inhalation | 31000ppm/30M (31000ppm) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Experimental Animals. Jikken Dobutso Iho. Vol. 34, Pg. 379, 1985. |
mouse | LD50 | intraperitoneal | 2420mg/kg (2420mg/kg) | Proceedings of the Western Pharmacology Society. Vol. 27, Pg. 511, 1984. | |
mouse | LD50 | intravenous | 996mg/kg (996mg/kg) | Journal of Pharmaceutical Sciences. Vol. 67, Pg. 566, 1978. | |
mouse | LDLo | subcutaneous | 8mg/kg (8mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1295, 1935. | |
rabbit | LCLo | inhalation | 106000ppm (106000ppm) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1294, 1935. | |
rabbit | LD50 | skin | > 20mL/kg (20mL/kg) | American Industrial Hygiene Association Journal. Vol. 23, Pg. 95, 1962. | |
rat | LCLo | inhalation | 32000ppm/4H (32000ppm) | American Industrial Hygiene Association Journal. Vol. 23, Pg. 95, 1962. | |
rat | LD50 | oral | 1215mg/kg (1215mg/kg) | Toxicology and Applied Pharmacology. Vol. 19, Pg. 699, 1971. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | -1.16E+02 | deg C | EXP | |
Boiling Point | 34.5 | deg C | EXP | |
pKa Dissociation Constant | -3.59E+00 | (none) | EXP | |
log P (octanol-water) | 0.89 | (none) | EXP | |
Water Solubility | 6.04E+04 | mg/L | 25 | EXP |
Vapor Pressure | 538 | mm Hg | 25 | EXP |
Henry's Law Constant | 0.00123 | atm-m3/mole | 25 | EXP |
Atmospheric OH Rate Constant | 1.31E-11 | cm3/molecule-sec | 25 | EXP |
Physical property data is provided to ChemIDplus by SRC, Inc.