Skip Navigation
ChemIDplus LiteBrowseAdvanced

Substance Name: Fenoprofen calcium [USAN:USP:BAN:JAN]
RN: 53746-45-5
UNII: 0X2CW1QABJ
InChIKey: LZPBLUATTGKZBH-UHFFFAOYSA-L

Classification Codes

  • Analgesic
  • Anti-Inflammatory
  • Drug / Therapeutic Agent
  • Human Data
  • Reproductive Effect

Molecular Formulas

  • C30-H26-Ca-O6.2H2-O
  • C30-H26-O6.Ca.2H2-O

Molecular Weight

  • 558.637
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Fenoprofen calcium [USAN:USP:BAN:JAN]

Synonyms

  • (+-)-alpha-Methyl-3-phenoxybenzeneacetic acid calcium salt dihydrate
  • 69323
  • Calcium (+-)-m-phenoxyhydratropate dihydrate
  • Calcium 2-(m-phenoxyphenyl)propionate dihydrate
  • Fenoprofen calcium
  • Fenoprofen calcium dihydrate
  • Fenoprofen calcium salt dihydrate
  • Fenopron
  • Feprona
  • Lilly 69323
  • Nalfon
  • Nalgesic
  • Progesic
  • Propionic acid, 2-(3-phenoxyphenyl)-, calcium salt, dihydrate, dl-
  • UNII-0X2CW1QABJ
  • YM-09229

Systematic Name

  • Benzeneacetic acid, alpha-methyl-3-phenoxy-, calcium salt dihydrate, (+-)-

Registry Numbers

CAS Registry Number

  • 53746-45-5

FDA UNII

  • 0X2CW1QABJ

Related Registry Number

  • 31879-05-7 (Parent)

System Generated Number

  • 0053746455

Molecular Formulas

Molecular Formulas

  • C30-H26-Ca-O6.2H2-O
  • C30-H26-O6.Ca.2H2-O

Molecular Formula Fragments

  • C30-H26-Ca-O6
  • C30-H26-O6
  • Ca
  • COMPONENT
  • H2-O

Structure Descriptors

InChI

1S/2C15H14O3.Ca.2H2O/c2*1-11(15(16)17)12-6-5-9-14(10-12)18-13-7-3-2-4-8-13;;;/h2*2-11H,1H3,(H,16,17);;2*1H2/q;;+2;;/p-2

InChIKey

LZPBLUATTGKZBH-UHFFFAOYSA-L

Smiles

[Ca+2].c1(cc(ccc1)[C@@H](C([O-])=O)C)Oc1ccccc1.c1(cc(ccc1)[C@@H](C([O-])=O)C)Oc1ccccc1.O.O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo oral 521mg/kg/17W- (521mg/kg) KIDNEY, URETER, AND BLADDER: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION
Annals of Internal Medicine. Vol. 93, Pg. 508, 1980.
mouse LD50 intraperitoneal 286mg/kg (286mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Yakkyoku. Pharmacy. Vol. 34, Pg. 363, 1983.
mouse LD50 intravenous 471mg/kg (471mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Yakkyoku. Pharmacy. Vol. 34, Pg. 363, 1983.
mouse LD50 oral 439mg/kg (439mg/kg)   Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 21, Pg. 36, 1986.
mouse LD50 subcutaneous 463mg/kg (463mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Yakkyoku. Pharmacy. Vol. 34, Pg. 363, 1983.
rat LD50 intraperitoneal 234mg/kg (234mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE

BLOOD: NORMOCYTIC ANEMIA

GASTROINTESTINAL: OTHER CHANGES
Yakkyoku. Pharmacy. Vol. 34, Pg. 363, 1983.
rat LD50 intravenous 526mg/kg (526mg/kg) BLOOD: NORMOCYTIC ANEMIA

GASTROINTESTINAL: OTHER CHANGES

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
Yakkyoku. Pharmacy. Vol. 34, Pg. 363, 1983.
rat LD50 oral 415mg/kg (415mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER

BLOOD: NORMOCYTIC ANEMIA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 4385, 1980.
rat LD50 subcutaneous 366mg/kg (366mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 1128, 1982.
women LDLo oral 8748mg/kg/35W (8748mg/kg) KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
American Journal of Medicine. Vol. 72, Pg. 81, 1982.
women TDLo oral 720mg/kg/30D- (720mg/kg) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" JAMA, Journal of the American Medical Association. Vol. 242, Pg. 1896, 1979.
women TDLo oral 1898mg/kg/12W (1898mg/kg) KIDNEY, URETER, AND BLADDER: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
Annals of Internal Medicine. Vol. 92, Pg. 72, 1980.
women TDLo oral 5832mg/kg/35W (5832mg/kg) KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS

GASTROINTESTINAL: NAUSEA OR VOMITING
American Journal of Medicine. Vol. 72, Pg. 81, 1982.