Substance Name: Rimabotulinumtoxinb [USAN]
RN: 93384-44-2
UNII: 0Y70779M1F
Note
- A neuromuscular agent used for the treatment of cervical dystonia.
Molecular Formula
- Unspecified
Classification Codes
- Acetylcholine Release Inhibitors
- Anti-Dyskinesia Agents
- Central Nervous System Agents
- Cholinergic Agents
- Membrane Transport Modulators
- Natural Product
- Neurotransmitter Agents
- Treatment of Cervical Dystonia
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Names and Synonyms
Name of Substance
- RimabotulinumtoxinB
- Rimabotulinumtoxinb [USAN]
Synonyms
- AN0772
- Botulin B
- Botulin toxin B
- BTX-B
- EINECS 297-255-5
- Myobloc
- NeuroBloc
- Rimabotulinumtoxinb
- UNII-0Y70779M1F
Systematic Names
- Botulin B
- Toxins, botulin, B
Registry Numbers
CAS Registry Number
- 93384-44-2
FDA UNII
- 0Y70779M1F
System Generated Number
- 0093384442
Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| domestic animals - goat/sheep | LDLo | oral | 34mg/kg (34mg/kg) | Annales de l'Institut Pasteur Vol. 72, Pg. 545, 1946. | |
| guinea pig | LDLo | subcutaneous | 5ug/kg (0.005mg/kg) | Annales de l'Institut Pasteur Vol. 71, Pg. 490, 1945. | |
| rabbit | LDLo | intramuscular | 50mg/kg (50mg/kg) | Annales de l'Institut Pasteur Vol. 71, Pg. 490, 1945. | |
| rabbit | LDLo | intraperitoneal | 50mg/kg (50mg/kg) | Annales de l'Institut Pasteur Vol. 71, Pg. 490, 1945. | |
| rabbit | LDLo | intravenous | 5ug/kg (0.005mg/kg) | Annales de l'Institut Pasteur Vol. 71, Pg. 490, 1945. | |
| rabbit | LDLo | oral | 50mg/kg (50mg/kg) | Annales de l'Institut Pasteur Vol. 71, Pg. 490, 1945. | |
| rabbit | LDLo | rectal | 50mg/kg (50mg/kg) | Annales de l'Institut Pasteur Vol. 71, Pg. 490, 1945. | |
| rabbit | LDLo | subcutaneous | 50mg/kg (50mg/kg) | Annales de l'Institut Pasteur Vol. 71, Pg. 490, 1945. |