Substance Name: Mavrilimumab [USAN:INN]
RN: 1085337-57-0
UNII: 1158JD1P9A
Note
- A human monoclonal antibody targeting GM-CSF receptor-alpha for treatment of rheumatoid arthritis.
Molecular Formula
- C6706-H10438-N1762-O2104-S54
Classification Codes
- Antirheumatic Agents
- Antiviral (COVID-19)
- Treatment of Rheumatoid Arthritis
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Links to Resources
NLM Resources (File Locators)
Other Resources (Internet Locators)
Names and Synonyms
Name of Substance
- Mavrilimumab [USAN:INN]
Synonyms
- CAM-3001
- CAM3001
- Immunoglobulin G4-lambda, anti-(Homo sapiens CSF2RA(granulocyte-macrophage colony-stimulating factor receptor subunit alpha, GM-CSF-R-alpha, CD116)), Homo sapiens monoclonal antibody; gamma4 heavy chain (1-447) (Homo sapiens VH (IGHV1-24*01 (93.80%) -(IGHD)-IGHJ3*02) (8.8.13) (1-120) -IGHG4*01 (121-447)), (134-216')-disulfide with lambda light chain (1'-217') (Homo sapiens V-LAMBDA (IGLV1-40*01 (87.90%) -IGLJ2*01) (9.3.11) (1'-111') - IGLC2*01 (112'-217')); (226- 226'':229-229'')-bisdisulfide dimer
- Mavrilimumab
- UNII-1158JD1P9A
Systematic Names
- Immunoglobulin G4, anti-(human granulocyte-macrophage colony-stimulating-factor receptor alpha-chain) (human monoclonal CAM-3001 heavy chain), disulfide with human monoclonal CAM-3001 gamma-chain, dimer
- Immunoglobulin G4, anti-(human granulocyte-macrophage colony-stimulating-factor receptor alpha-chain) (human monoclonal CAM-3001 heavy chain), disulfide with human monoclonal CAM-3001 lambda-chain, dimer
Registry Numbers
CAS Registry Number
- 1085337-57-0
FDA UNII
- 1158JD1P9A
System Generated Number
- 1085337570