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Substance Name: Cefpiramide sodium [USAN:JAN]
RN: 74849-93-7
UNII: 137KB7GYKB
InChIKey: RIWWMGQFMUUYIY-ALLHVENQSA-M

Classification Codes

  • Antibacterial
  • Drug / Therapeutic Agent
  • Mutation Data
  • Reproductive Effect

Molecular Formulas

  • C25-H23-N8-Na-O7-S2
  • C25-H23-N8-O7-S2.Na

Molecular Weight

  • 634.6277
 
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Names and Synonyms

Name of Substance

  • Cefpiramide sodium [USAN:JAN]

Synonyms

  • 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((((4-hydroxy-6-methyl-3-pyridinyl)carbonyl)amino)(4-hydroxyphenyl)acetyl)amino)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, monosodium salt, (6R-(6alpha,7beta(R*)))-
  • Antibiotic SM 1652
  • Cefpiramide sodium
  • SM 1652
  • SM-1652
  • Sodium (6R,7R)-7-((R)-2-(4-hydroxy-6-methylnicotinamido)-2-(p-hydroxyphenyl)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate
  • UNII-137KB7GYKB
  • WY 44,635 sodium
  • WY-44,635 sodium

Systematic Name

  • 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((((4-hydroxy-6-methyl-3-pyridinyl)carbonyl)amino)(4-hydroxyphenyl)acetyl)amino)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, monosodium salt, (6R-(6alpha,7beta(R*)))-

Registry Numbers

CAS Registry Number

  • 74849-93-7

FDA UNII

  • 137KB7GYKB

Related Registry Number

  • 70797-11-4 (Parent)

System Generated Number

  • 0074849937

Molecular Formulas

Molecular Formulas

  • C25-H23-N8-Na-O7-S2
  • C25-H23-N8-O7-S2.Na

Molecular Formula Fragments

  • C25-H23-N8-O7-S2
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C25H24N8O7S2.Na/c1-11-7-16(35)15(8-26-11)20(36)27-17(12-3-5-14(34)6-4-12)21(37)28-18-22(38)33-19(24(39)40)13(9-41-23(18)33)10-42-25-29-30-31-32(25)2;/h3-8,17-18,23,34H,9-10H2,1-2H3,(H,26,35)(H,27,36)(H,28,37)(H,39,40);/q;+1/p-1/t17-,18-,23-;/m1./s1

InChIKey

RIWWMGQFMUUYIY-ALLHVENQSA-M

Smiles

[Na+].Cc1cc(O)c(cn1)C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)[O-])CSc4nnnn4C)c5ccc(O)cc5

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intramuscular 1250mg/kg (1250mg/kg)   Drugs in Japan Vol. -, Pg. 578, 1990.
mouse LD50 intraperitoneal 6400mg/kg (6400mg/kg)   Drugs in Japan Vol. -, Pg. 678, 1995.
mouse LD50 intravenous 4300mg/kg (4300mg/kg)   Drugs in Japan Vol. -, Pg. 578, 1990.
mouse LD50 subcutaneous 8800mg/kg (8800mg/kg)   Drugs in Japan Vol. -, Pg. 678, 1995.
rat LD50 intramuscular > 1250mg/kg (1250mg/kg)   Drugs in Japan Vol. -, Pg. 678, 1995.
rat LD50 intraperitoneal 12200mg/kg (12200mg/kg)   Drugs in Japan Vol. -, Pg. 578, 1990.
rat LD50 intravenous 5850mg/kg (5850mg/kg)   Drugs in Japan Vol. -, Pg. 578, 1990.
rat LD50 oral 12500mg/kg (12500mg/kg)   Drugs in Japan Vol. -, Pg. 578, 1990.
rat LD50 subcutaneous > 10gm/kg (10000mg/kg)   Drugs in Japan Vol. -, Pg. 678, 1995.