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Substance Name: Tribromoethanol [NF]
RN: 75-80-9
UNII: 149JI83A44
InChIKey: YFDSDPIBEUFTMI-UHFFFAOYSA-N
Classification Codes
- Anesthetics
- Central Nervous System Agents
- Central Nervous System Depressants
- Drug / Therapeutic Agent
- Mutation Data
Molecular Formula
- C2-H3-Br3-O
Molecular Weight
- 282.757
- All
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
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Names and Synonyms
Name of Substance
- Tribromoethanol [NF]
Synonyms
- 2,2,2-Tribromoethanol
- 2,2,2-Tribromoethyl alcohol
- 3-01-00-01362 (Beilstein Handbook Reference)
- Avertin
- Avertine
- Basibrol
- BRN 1733249
- Bromethol
- EINECS 200-903-1
- Ethobrom
- Ethobrome
- Narcolan
- Narcotyl
- Narkolan
- NSC 2189
- Rectanol
- Tribromethanol
- Tribromoethanol
- Tribromoethanol (VAN)
- Tribromoethyl alcohol
- UNII-149JI83A44
Systematic Names
- 2,2,2-Tribromoethanol
- Ethanol, 2,2,2-tribromo-
Registry Numbers
CAS Registry Number
- 75-80-9
FDA UNII
- 149JI83A44
Other Registry Number
- 8002-84-4
System Generated Number
- 0000075809
Structure Descriptors
InChI
InChI=1S/C2H3Br3O/c3-2(4,5)1-6/h6H,1H2InChIKey
YFDSDPIBEUFTMI-UHFFFAOYSA-NSmiles
OCC(Br)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | oral | 930mg/kg (930mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Journal of Pharmaceutical Sciences. Vol. 56, Pg. 920, 1967. |
| rabbit | LDLo | intraperitoneal | 450mg/kg (450mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: GENERAL ANESTHETIC | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 132, Pg. 214, 1928. |
| rabbit | LDLo | oral | 1100mg/kg (1100mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: GENERAL ANESTHETIC | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 132, Pg. 214, 1928. |
| rabbit | LDLo | rectal | 300mg/kg (300mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 55, Pg. 1, 1935. | |
| rat | LDLo | intraperitoneal | 300mg/kg (300mg/kg) | Laboratory Animal Science. Vol. 49, Pg. 665, 1999. | |
| rat | LDLo | intraperitoneal | 300mg/kg (300mg/kg) | LIVER: "HEPATITIS, FIBROUS (CIRRHOSIS, POST-NECROTIC SCARRING)" GASTROINTESTINAL: OTHER CHANGES | Laboratory Animal Science. Vol. 49, Pg. 665, 1999. |
| rat | LDLo | oral | 1gm/kg (1000mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 63, Pg. 183, 1938. | |
| rat | LDLo | subcutaneous | 530mg/kg (530mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 182, Pg. 348, 1936. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 81 | deg C | EXP | |
| log P (octanol-water) | 2.1 | (none) | EXP | |
| Water Solubility | 3.40E+04 | mg/L | 40 | EXP |
| Vapor Pressure | 1.72E-03 | mm Hg | 25 | EST |
| Henry's Law Constant | 5.47E-09 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 3.69E-13 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.