Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Fosenazide [INN]
RN: 16543-10-5
UNII: 16C19Z7F4I
InChIKey: PMHFLBQRALFMRT-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C14-H15-N2-O2-P

Molecular Weight

  • 274.2585
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Fosenazide [INN]
  • Gidifen

Synonyms

  • BRN 2743655
  • Diphenyl phosphinyl acetic acid hydrazide
  • Diphenylphosphinyl acethydrazide
  • Diphenylphosphinylessigsaeurehydrazid
  • Diphenylphosphinylessigsaeurehydrazid [German]
  • Fosenazida
  • Fosenazida [INN-Spanish]
  • Fosenazide
  • Fosenazidum
  • Fosenazidum [INN-Latin]
  • Gidifen
  • Hydifen
  • Phosphabenzide
  • UNII-16C19Z7F4I

Systematic Names

  • (Diphenylphosphinyl)acetic acid, hydrazide
  • Acetic acid, (diphenylphosphinyl)-, hydrazide

Registry Numbers

CAS Registry Number

  • 16543-10-5

FDA UNII

  • 16C19Z7F4I

System Generated Number

  • 0016543105

Structure Descriptors

InChI

1S/C14H15N2O2P/c15-16-14(17)11-19(18,12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10H,11,15H2,(H,16,17)

InChIKey

PMHFLBQRALFMRT-UHFFFAOYSA-N

Smiles

c1ccc(cc1)P(=O)(CC(=O)NN)c2ccccc2

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LD50 intraperitoneal 315mg/kg (315mg/kg) BEHAVIORAL: ANTIPSYCHOTIC

BEHAVIORAL: ANALGESIA

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Russian Pharmacology and Toxicology Vol. 43, Pg. 122, 1980.
mouse LD50 intraperitoneal 315mg/kg (315mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Pharmaceutical Chemistry Journal Vol. 20, Pg. 315, 1986.
mouse LD50 intravenous 293mg/kg (293mg/kg)   German Offenlegungsschrift Patent Document. Vol. #2751389,