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Substance Name: Enfuvirtide [USAN:INN:BAN]
RN: 159519-65-0
UNII: 19OWO1T3ZE
InChIKey: PEASPLKKXBYDKL-FXEVSJAOSA-N
Notes
- A synthetic 36-amino acid peptide that corresponds to the heptad repeat sequence of HIV-1 gp41. It blocks HIV cell fusion and viral entry and is used with other anti-retrovirals for combination therapy of HIV INFECTIONS and AIDS.
- Corresponds to the heptad repeat sequence of HIV-1 gp41.
AIDSinfo: Enfuvirtide is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 6 years of age and older. Enfuvirtide is for people who have not responded well enough to treatment with other anti-HIV medicines. Enfuvirtide is always used in combination with other anti-HIV medicines.
Molecular Formula
- C204-H301-N51-O64
Molecular Weight
- 4491.9149
Classification Codes
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral (Blockade of Gp-41 Mediated Membrane Fusion)
- Antiviral (COVID-19)
- Antiviral Agents
- Fusion Inhibitor
- HIV Fusion Inhibitors
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Names and Synonyms
Name of Substance
- Enfuvirtide
- Enfuvirtide [USAN:INN:BAN]
MeSH Heading
- Enfuvirtide
Synonyms
- DP 178
- DP-178
- DP178
- Enfuvirtide
- Fuzeon
- HSDB 7341
- L-Phenylalaninamide, N-acetyl-L-tyrosyl-L-threonyl-L-seryl-L-leucyl-L-isoleucyl-L-histadyl-L-seryl-L-leucyl-L-isoleucyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-glutaminyl-L-asparaginyl-L-glutaminyl-L-glutaminyl-L-alpha-glutamyl-L-lysyl-L-asparaginyl-L-alpha-glutamyl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-leucyl-L-alpha-glutamyl-L-leucyl-L-alpha-aspartyl-L-lysyl-L-tryptophyl-L-alanyl-L-seryl-L-leucyl-L-tryptophyl-L-asparaginyl-L-tryptophyl-
- N-Acetyl-L-tyrosyl-L-threonyl-L-seryl-L-leucyl-L-isoleucyl-L-histadyl-L-seryl-L-leucyl-L-isoleucyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-glutaminyl-L-asparaginyl-L-glutaminyl-L-glutaminyl-L-alpha-glutamyl-L-lysyl-L-asparaginyl-L-alpha-glutamyl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-leucyl-L-alpha-glutamyl-L-leucyl-L-alpha-aspartyl-L-lysyl-L-tryptophyl-L-alanyl-L-seryl-L-leucyl-L-tryptophyl-L-asparaginyl-L-tryptophyl-L-phenylalaninamide
- Pentafuside
- T 20
- T 20 (peptide)
- T-20
- T20
- UNII-19OWO1T3ZE
Systematic Name
- L-Phenylalaninamide, N-acetyl-L-tyrosyl-L-threonyl-L-seryl-L-leucyl-L-isoleucyl-L-histidyl-L-seryl-L-leucyl-L-isoleucyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-glutaminyl-L-asparaginyl-L-glutaminyl-L-glutaminyl-L-alpha-glutamyl-L-lysyl-L-asparaginyl-L-alpha-glutamyl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-leucyl-L-alpha-glutamyl-L-leucyl-L-alpha-aspartyl-L-lysyl-L-tryptophyl-L-alanyl-L-seryl-L-leucyl-L-tryptophyl-L-asparaginyl-L-tryptophyl-
Registry Numbers
CAS Registry Number
- 159519-65-0
FDA UNII
- 19OWO1T3ZE
Other Registry Number
- 262434-79-7
System Generated Number
- 0159519650