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Substance Name: dl-threo-Methylphenidate
RN: 20748-11-2
UNII: 207ZZ9QZ49
InChIKey: DUGOZIWVEXMGBE-STQMWFEESA-N
Note
- A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
Molecular Formula
- C14-H19-N-O2
Molecular Weight
- 233.3091
Classification Codes
- Central Nervous System Agents
- Central Nervous System Stimulants
- Dopamine Agents
- Dopamine Uptake Inhibitors
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
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Names and Synonyms
Name of Substance
- dl-threo-Methylphenidate
MeSH Heading
- Methylphenidate
Synonyms
- Methyl alpha-phenyl-2-piperidineacetate
- threo-(+-)-Methylphenidate
- threo-Methylphenidate
- UNII-207ZZ9QZ49
Systematic Name
- 2-Piperidineacetic acid, alpha-phenyl-, methyl ester, stereoisomer
Registry Numbers
CAS Registry Number
- 20748-11-2
FDA UNII
- 207ZZ9QZ49
Other Registry Numbers
- 52760-39-1
- 73790-87-1
System Generated Number
- 0020748112
Structure Descriptors
InChI
InChI=1S/C14H19NO2/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3/t12-,13-/m0/s1InChIKey
DUGOZIWVEXMGBE-STQMWFEESA-NSmiles
COC(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 39mg/kg (39mg/kg) | BEHAVIORAL: WAKEFULNESS BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Biochemical Pharmacology. Vol. 8, Pg. 263, 1961. |
mouse | LD50 | intravenous | 39mg/kg (39mg/kg) | BEHAVIORAL: WAKEFULNESS BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Biochemical Pharmacology. Vol. 8, Pg. 263, 1961. |