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Substance Name: Picoperine hydrochloride
RN: 24699-40-9
UNII: 2142K55R4Y
InChIKey: MSVZUEGLXXVUJS-UHFFFAOYSA-N
Classification Codes
- Drug / Therapeutic Agent
- Reproductive Effect
Molecular Formula
- C19-H25-N3.Cl-H
Molecular Weight
- 331.888
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Names and Synonyms
Name of Substance
- Picoperine hydrochloride
Synonyms
- 1-(2-(N-(2-Pyridylmethyl)anilino)ethyl)piperidine hydrochloride
- 1-(2-(Phenyl(2-pyridylmethyl)amino)ethyl)piperidine hydrochloride
- 2-Pyridinemethanamine, N-phenyl-N-(2-(1-piperidinyl)ethyl)-, monohydrochloride
- Coben
- N-(2-Picolyl)-N-phenyl-N-(2-piperidinoethyl)amine hydrochloride
- N-(2-Piperidinoethyl)-N-(2-pyridylmethyl)aniline hydrochloride
- N-(2-Pyridylmethyl)-N-phenyl-N-2-(piperidinoethyl)amine hydrochloride
- N-Phenyl-N-(2-pyridylmethyl)-2-piperidinoethylamine hydrochloride
- Picoperidamine hydrochloride
- Picoperine HCl
- Picoperine hydrochloride
- Piperidine, 1-(2-(N-(2-pyridylmethyl)anilino)ethyl)-, monohydrochloride
- TAT-3 hydrochloride
- UNII-2142K55R4Y
Systematic Name
- Piperidine, 1-(2-(N-(2-pyridylmethyl)anilino)ethyl)-, hydrochloride
Registry Numbers
CAS Registry Number
- 24699-40-9
FDA UNII
- 2142K55R4Y
Other Registry Number
- 21755-67-9
Related Registry Number
- 21755-66-8 (Parent)
System Generated Number
- 0024699409
Molecular Formulas
Molecular Formula
- C19-H25-N3.Cl-H
Molecular Formula Fragments
- C19-H25-N3
- Cl-H
- COMPONENT
Structure Descriptors
InChI
1S/C19H25N3.ClH/c1-3-10-19(11-4-1)22(17-18-9-5-6-12-20-18)16-15-21-13-7-2-8-14-21;/h1,3-6,9-12H,2,7-8,13-17H2;1HInChIKey
MSVZUEGLXXVUJS-UHFFFAOYSA-NSmiles
c1(ccccn1)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LDLo | intravenous | 25mg/kg (25mg/kg) | GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS | Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1916, 1969. |
dog | LDLo | oral | 100mg/kg (100mg/kg) | LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1916, 1969. |
mouse | LD50 | intraperitoneal | 55500ug/kg (55.5mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. | |
mouse | LD50 | intravenous | 10mg/kg (10mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. | |
mouse | LD50 | oral | 195mg/kg (195mg/kg) | Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 29, Pg. 310, 1970. | |
mouse | LD50 | subcutaneous | 142mg/kg (142mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. |
rat | LD50 | intraperitoneal | 69mg/kg (69mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. | |
rat | LD50 | intravenous | 11500ug/kg (11.5mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. | |
rat | LD50 | oral | 740mg/kg (740mg/kg) | BEHAVIORAL: EXCITEMENT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. |
rat | LD50 | subcutaneous | 480mg/kg (480mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. |