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Substance Name: Phenol [USP:JAN]
RN: 108-95-2
UNII: 339NCG44TV
InChIKey: ISWSIDIOOBJBQZ-UHFFFAOYSA-N
Note
- An antiseptic and disinfectant aromatic alcohol.
Molecular Formula
- C6-H6-O
Molecular Weight
- 94.1124
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Agricultural Chemical
- Anti-Infective Agents
- Anti-Infective Agents, Local
- Cardiovascular Agents
- Disinfectants
- Germicide, Bactericide, Disinfectant
- Human Data
- Mutation Data
- Pharmaceutic Aid (Preservative)
- Pharmaceutical Solutions
- Reproductive Effect
- Sclerosing Solutions
- Skin / Eye Irritant
- Tumor Data
Superlist Classification Codes
- 2007 CERCLA Priority List, Rank: 182
- 2011 CERCLA Priority List, Rank: 179
- Overall Carcinogenic Evaluation: Group 3
- Reportable Quantity (RQ) = 1000 lb
- Threshold Planning Quantity (TPQ) = 500/10000 lb
- TWA 5 ppm (19 mg/m3); skin
- TWA(5 ppm); skin; Not classifiable as a human carcinogen; BEI
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Other Resources (Internet Locators)
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Names and Synonyms
Name of Substance
- Carbolic acid
- Liquid phenol
- Phenol
- Phenol [USP:JAN]
MeSH Heading
- Phenol
Synonyms
- Acide carbolique
- Acide carbolique [French]
- AI3-01814
- Baker's P & S liquid & Ointment
- Baker's P and S Liquid and Ointment
- Benzenol
- Carbolic acid
- Carbolsaure
- Carbolsaure [German]
- Caswell No. 649
- CCRIS 504
- EC 203-632-7
- EINECS 203-632-7
- EPA Pesticide Chemical Code 064001
- FEMA No. 3223
- Fenol
- Fenol [Dutch, Polish]
- Fenolo
- Fenolo [Italian]
- HSDB 113
- Hydroxybenzene
- Izal
- Monohydroxybenzene
- Monophenol
- NCI-C50124
- NSC 36808
- Oxybenzene
- Paoscle
- Phenic acid
- Phenol
- Phenol alcohol
- Phenol, liquefied
- Phenole
- Phenole [German]
- Phenyl alcohol
- Phenyl hydrate
- Phenyl hydroxide
- Phenylic acid
- Phenylic alcohol
- PhOH
- RCRA waste number U188
- UN 1671 (solid)
- UN 2312 (molten)
- Un 2812 (solution)
- UNII-339NCG44TV
Systematic Names
- Phenol
- Phenol, pure
Superlist Names
- Benzene, hydroxy-
- Carbolic oil
- Phenol
- Phenol (or solutions with 5% or more phenol)
- Phenol solutions
- Phenol solutions [UN2821] [Poison]
- Phenol, molten
- Phenol, molten [UN2312] [Poison]
- Phenol, solid
- Phenol, solid [UN1671] [Poison]
- RCRA waste no. U188
- UN1671
- UN2312
- UN2821
Mixture Names
- Campho-Phenique Cold Sore Gel
- Campho-Phenique Gel
- Campho-Phenique Liquid
Registry Numbers
CAS Registry Number
- 108-95-2
FDA UNII
- 339NCG44TV
Other Registry Numbers
- 14534-23-7
- 50356-25-7
- 8002-07-1
Related Registry Number
- 139-02-6 (hydrochloride salt)
System Generated Number
- 0000108952
Structure Descriptors
InChI
InChI=1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7HInChIKey
ISWSIDIOOBJBQZ-UHFFFAOYSA-NSmiles
Oc1ccccc1Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LDLo | oral | 80mg/kg (80mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1319, 1935. | |
cat | LDLo | subcutaneous | 80mg/kg (80mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 233, 1944. | |
cat | LDLo | unreported | 250mg/kg (250mg/kg) | Revue Medicale de la Suisse Romande. Vol. 15, Pg. 561, 1895. | |
dog | LDLo | oral | 500mg/kg (500mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1319, 1935. | |
dog | LDLo | unreported | 200mg/kg (200mg/kg) | Revue Medicale de la Suisse Romande. Vol. 15, Pg. 561, 1895. | |
frog | LDLo | parenteral | 290mg/kg (290mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD CARDIAC: OTHER CHANGES PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 166, Pg. 437, 1932. |
frog | LDLo | subcutaneous | 75mg/kg (75mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1319, 1935. | |
frog | LDLo | subcutaneous | 290mg/kg (290mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 228, 1955. | |
guinea pig | LDLo | intraperitoneal | 300mg/kg (300mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 228, 1955. | |
guinea pig | LDLo | subcutaneous | 450mg/kg (450mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 228, 1955. | |
human | LDLo | oral | 140mg/kg (140mg/kg) | SKIN AND APPENDAGES (SKIN): SWEATING: OTHER BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" | "Practical Toxicology of Plastics," Lefaux, R., Cleveland, OH, Chemical Rubber Co., 1968Vol. -, Pg. 329, 1968. |
human | LDLo | oral | 14gm/kg (14000mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: CYANOSIS | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 463, 1969. |
infant | LDLo | oral | 10mg/kg (10mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: CYANOSIS | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 463, 1969. |
mammal (species unspecified) | LD50 | oral | 500mg/kg (500mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988. | |
man | TDLo | unreported | 5714ug/kg (5.714mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION | Veterinary and Human Toxicology. Vol. 41, Pg. 151, 1999. |
mouse | LC50 | inhalation | 177mg/m3 (177mg/m3) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 41(6), Pg. 103, 1976. | |
mouse | LD50 | intraperitoneal | 180mg/kg (180mg/kg) | Pharmacologist. Vol. 10, Pg. 172, 1968. | |
mouse | LD50 | intravenous | 112mg/kg (112mg/kg) | BEHAVIORAL: TREMOR | Quarterly Journal of Pharmacy & Pharmacology. Vol. 12, Pg. 212, 1939. |
mouse | LD50 | oral | 270mg/kg (270mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 38(8), Pg. 6, 1973. | |
mouse | LD50 | subcutaneous | 344mg/kg (344mg/kg) | Industrial Health. Vol. 5, Pg. 143, 1967. | |
rabbit | LD50 | skin | 630mg/kg (630mg/kg) | Union Carbide Data Sheet. Vol. 1/6/1966, | |
rabbit | LDLo | intraperitoneal | 620mg/kg (620mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 233, 1944. | |
rabbit | LDLo | intravenous | 180mg/kg (180mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 233, 1944. | |
rabbit | LDLo | oral | 420mg/kg (420mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 233, 1944. | |
rabbit | LDLo | subcutaneous | 620mg/kg (620mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 233, 1944. | |
rabbit | LDLo | unreported | 150mg/kg (150mg/kg) | Revue Medicale de la Suisse Romande. Vol. 15, Pg. 561, 1895. | |
rat | LC50 | inhalation | 316mg/m3 (316mg/m3) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 41(6), Pg. 103, 1976. | |
rat | LD50 | intraperitoneal | 127mg/kg (127mg/kg) | Food and Chemical Toxicology. Vol. 22, Pg. 665, 1984. | |
rat | LD50 | oral | 317mg/kg (317mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Proceedings of the Society for Experimental Biology and Medicine. Vol. 32, Pg. 592, 1935. |
rat | LD50 | skin | 669mg/kg (669mg/kg) | KIDNEY, URETER, AND BLADDER: HEMATURIA SKIN AND APPENDAGES (SKIN): CUTANEOUS SENSITIZATION (EXPERIMENTAL): AFTER TOPICAL EXPOSURE BEHAVIORAL: TREMOR | British Journal of Industrial Medicine. Vol. 27, Pg. 155, 1970. |
rat | LD50 | subcutaneous | 460mg/kg (460mg/kg) | Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 10, Pg. 1, 1963. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 40.9 | deg C | EXP | |
Boiling Point | 181.8 | deg C | EXP | |
pKa Dissociation Constant | 9.994 | (none) | 25 | EXP |
log P (octanol-water) | 1.46 | (none) | EXP | |
Water Solubility | 8.28E+04 | mg/L | 25 | EXP |
Vapor Pressure | 0.35 | mm Hg | 25 | EXP |
Henry's Law Constant | 3.33E-07 | atm-m3/mole | 25 | EXP |
Atmospheric OH Rate Constant | 2.63E-11 | cm3/molecule-sec | 25 | EXP |
Physical property data is provided to ChemIDplus by SRC, Inc.