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Substance Name: Glutamic Acid [USAN:INN]
RN: 56-86-0
UNII: 3KX376GY7L
InChIKey: WHUUTDBJXJRKMK-VKHMYHEASA-N
Note
- A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.
Molecular Formula
- C5-H9-N-O4
Molecular Weight
- 147.1291
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- Registry Numbers
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- Toxicity
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Classification Codes
- Antiviral (COVID-19)
- Human Data
- Mutation Data
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Names and Synonyms
Name of Substance
- Glutamic acid
- Glutamic Acid [USAN:INN]
MeSH Heading
- Glutamic acid
Synonyms
- 1-Aminopropane-1,3-dicarboxylic acid
- 2-Aminopentanedioic acid
- 2-Aminopentanedioic acid, (S)-
- Acide glutamique
- Acide glutamique [INN-French]
- Acido glutamico
- Acido glutamico [INN-Spanish]
- Acidum glutamicum
- Acidum glutamicum [INN-Latin]
- Acidum glutaminicum
- Aciglut
- AI3-18472
- alpha-Aminoglutaric acid
- alpha-Aminoglutaric acid (VAN)
- CCRIS 7314
- D-Glutamiensuur
- EC 200-293-7
- EINECS 200-293-7
- EPA Pesticide Chemical Code 374350
- FEMA No. 3285
- Glusate
- Glutacid
- Glutamate, L-
- Glutamic acid
- Glutamic acid (H-3)
- Glutamic acid (VAN)
- Glutamic acid, (S)-
- Glutamicol
- Glutamidex
- Glutaminic acid
- Glutaminic acid (VAN)
- Glutaminol
- Glutaton
- HSDB 490
- L-2-Aminoglutaric acid
- L-Acido glutamico
- L-Glutamic acid
- L-Glutaminic acid
- NSC 143503
- Pentanedioic acid, 2-amino-, (S)-
- UNII-3KX376GY7L
Systematic Names
- Glutamic acid
- L-Glutamic acid
Superlist Names
- Glutamic acid, L-
- L-Glutamic acid
Registry Numbers
CAS Registry Number
- 56-86-0
FDA UNII
- 3KX376GY7L
Other Registry Numbers
- 10549-13-0
- 138-16-9
- 2087491-17-4
- 6899-05-4
Related Registry Numbers
- 138-15-8 (unspecified hydrochloride)
- 16690-92-9 (di-hydrochloride salt)
- 19238-49-4 (unspecified calcium salt)
- 19473-49-5 (mono-potassium salt)
- 24595-14-0 (unspecified potassium salt)
- 55695-80-2 (mono-lithium salt)
- 7558-63-6 (mono-ammonium salt)
System Generated Number
- 0000056860
Structure Descriptors
InChI
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1InChIKey
WHUUTDBJXJRKMK-VKHMYHEASA-NSmiles
N[C@@H](CCC(=O)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| human | TDLo | intravenous | 117mg/kg (117mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING | American Journal of the Medical Sciences. Vol. 214, Pg. 281, 1947. |
| human | TDLo | oral | 71mg/kg (71mg/kg) | BEHAVIORAL: HEADACHE | Science. Vol. 163, Pg. 826, 1969. |
| rabbit | LD50 | oral | > 2300mg/kg (2300mg/kg) | FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 42, 1970. | |
| rat | LD50 | oral | > 30gm/kg (30000mg/kg) | FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 42, 1970. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 224 dec | deg C | EXP | |
| pKa Dissociation Constant | 2.23 | (none) | 0 | EXP |
| log P (octanol-water) | -3.69E+00 | (none) | EXP | |
| Water Solubility | 8570 | mg/L | 25 | EXP |
| Henry's Law Constant | 1.47E-14 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 4.10E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.