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Substance Name: Ibogaine
RN: 83-74-9
UNII: 3S814I130U
InChIKey: HSIBGVUMFOSJPD-CFDPKNGZSA-N
Note
- One of several indole alkaloids extracted from Tabernanthe iboga, Baill. It has a complex pharmacological profile, and interacts with multiple systems of neurotransmission. Ibogaine has psychoactive properties and appears to modulate tolerance to opiates.
Molecular Formula
- C20-H26-N2-O
Molecular Weight
- 310.4384
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Central Nervous System Agents
- Drug / Therapeutic Agent
- Excitatory Amino Acid Agents
- Excitatory Amino Acid Antagonists
- Hallucinogens
- Natural Product
- Neurotransmitter Agents
- Psychotropic Drugs
Superlist Classification Code
- DEA Schedule I
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Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
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Names and Synonyms
Name of Substance
- Ibogaine
MeSH Heading
- Ibogaine
Synonyms
- (-)-Ibogaine
- 12-Methoxyibogamine
- EINECS 201-498-4
- Endabuse
- HSDB 8180
- Ibogain
- Ibogaine
- NIH 10567
- NSC 249764
- UNII-3S814I130U
Systematic Names
- 12-Methoxyibogamine
- Ibogaine (8CI)
- Ibogamine, 12-methoxy-
Superlist Names
- 7-Ethyl-6,6beta,7,8,9,10,12,13-octahydro-2-methoxy-6,9-methano-5H-pyrido(1',2':1,2)azepino(5,4-b)indole
- DEA No. 7260
- Ibogaine
- Tabernanthe iboga
Registry Numbers
CAS Registry Number
- 83-74-9
FDA UNII
- 3S814I130U
Other Registry Number
- 17378-46-0
System Generated Number
- 0000083749
Structure Descriptors
InChI
InChI=1S/C20H26N2O/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12-,13+,17+,20+/m1/s1InChIKey
HSIBGVUMFOSJPD-CFDPKNGZSA-NSmiles
CC[C@H]1C[C@@H]2C[C@@H]3[C@H]1N(CCc4c3[nH]c5ccc(OC)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | intraperitoneal | 82mg/kg (82mg/kg) | Drugs of the Future. Vol. 21, Pg. 1109, 1996. | |
rat | LD50 | intraperitoneal | 145mg/kg (145mg/kg) | Drugs of the Future. Vol. 21, Pg. 1109, 1996. | |
rat | LD50 | oral | 327mg/kg (327mg/kg) | Drugs of the Future. Vol. 21, Pg. 1109, 1996. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 148 | deg C | EXP | |
log P (octanol-water) | 3.650 | (none) | EST | |
Atmospheric OH Rate Constant | 2.34E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.