|
|
|
Substance Name: Clindamycin [USAN:INN:BAN]
RN: 18323-44-9
UNII: 3U02EL437C
InChIKey: KDLRVYVGXIQJDK-AWPVFWJPSA-N
Note
- An antibacterial agent that is a semisynthetic analog of LINCOMYCIN.
Molecular Formula
- C18-H33-Cl-N2-O5-S
Molecular Weight
- 424.9867
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antibacterial
- Drug / Therapeutic Agent
- Enzyme Inhibitors
- Protein Synthesis Inhibitors
* denotes mobile formatted website
Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Search for this InChIKey on the Web
Names and Synonyms
Name of Substance
- Clindamycin
- Clindamycin [USAN:INN:BAN]
MeSH Heading
- Clindamycin
Synonyms
- 7(S)-Chloro-7-deoxylincomycin
- 7-CDL
- 7-Chloro-7-deoxylincomycin
- 7-Chlorolincomycin
- 7-Deoxy-7(S)-chlorolincomycin
- Antirobe
- Chlolincocin
- Cleocin
- ClindaDerm
- Clindamicina
- Clindamicina [INN-Spanish]
- Clindamycin
- Clindamycine
- Clindamycine [French]
- Clindamycine [INN-French]
- Clindamycinum
- Clindamycinum [INN-Latin]
- Clinimycin
- Dalacin C
- Dalacine
- EINECS 242-209-1
- HSDB 3037
- Klimicin
- Klindan 300
- Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside
- Sobelin
- U 21251
- U-21,251
- UNII-3U02EL437C
Systematic Names
- Clindamycin
- L-threo-alpha-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-((((2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-
- L-threo-alpha-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, (2S-trans)-
- L-threo-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, trans-alpha-
Registry Numbers
CAS Registry Number
- 18323-44-9
FDA UNII
- 3U02EL437C
Other Registry Numbers
- 13441-63-9
- 16669-21-9
- 24620-78-8
- 24696-19-3
Related Registry Numbers
- 21462-39-5 (mono-hydrochloride)
- 58207-19-5 (mono-HCl, mono-hydrate)
System Generated Number
- 0018323449
Structure Descriptors
InChI
InChI=1S/C18H33ClN2O5S/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25)/t9-,10+,11-,12+,13-,14+,15+,16+,18+/m0/s1InChIKey
KDLRVYVGXIQJDK-AWPVFWJPSA-NSmiles
CCC[C@@H]1C[C@H](N(C)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| hamster | LDLo | oral | 1mg/kg (1mg/kg) | GASTROINTESTINAL: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 34, Pg. 794, 1984. |
| rabbit | LDLo | oral | 1mg/kg (1mg/kg) | Recueil de Medecine Veterinaire. Vol. 156, Pg. 915, 1980. | |
| rat | LD50 | subcutaneous | 2618mg/kg (2618mg/kg) | Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| log P (octanol-water) | 2.16 | (none) | EXP | |
| Water Solubility | 30.6 | mg/L | 25 | EST |
| Vapor Pressure | 5.28E-17 | mm Hg | 25 | EST |
| Henry's Law Constant | 2.89E-22 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 2.63E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.