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Substance Name: Candicidin [USAN:USP:INN:BAN]
RN: 1403-17-4
UNII: 48N2IYJ202
InChIKey: OPGSFDUODIJJGF-JBUZINEHSA-N
Note
- Mixture of antifungal heptaene macrolides from Streptomyces griseus or Actinomyces levoris used topically in candidiasis. The antibiotic complex is composed of candicidins A, B, C, and D, of which D is the major component.
Molecular Formula
- C63-H85-N21-O19
Molecular Weight
- 1109.3086
- All
- Classifications
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- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antifungal
- Antifungal Agents
- Drug / Therapeutic Agent
- Natural Product
- Reproductive Effect
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Names and Synonyms
Name of Substance
- Candicidin
- Candicidin [USAN:USP:INN:BAN]
MeSH Heading
- Candicidin
Synonyms
- Candeptin
- Candicidin
- Candicidina
- Candicidina [INN-Spanish]
- Candicidine
- Candicidine [INN-French]
- Candicidinum
- Candicidinum [INN-Latin]
- Candimon
- Candizidin
- Candizidin [German]
- EINECS 215-763-7
- Levorina
- Levorina [INN-Spanish]
- Levorine
- Levorine [INN-French]
- Levorinum
- Levorinum [INN-Latin]
- NSC 94219
- UNII-48N2IYJ202
- Vanobid
Systematic Name
- Candicidin
Registry Numbers
CAS Registry Number
- 1403-17-4
FDA UNII
- 48N2IYJ202
System Generated Number
- 0001403174
Structure Descriptors
InChI
InChI=1S/C59H84N2O18/c1-35-18-15-13-11-9-7-5-6-8-10-12-14-16-21-47(78-59-56(74)54(61)55(73)38(4)77-59)33-51(71)53(58(75)76)50(70)31-46(67)30-45(66)29-44(65)28-43(64)27-41(62)19-17-20-42(63)32-52(72)79-57(35)37(3)26-36(2)48(68)34-49(69)39-22-24-40(60)25-23-39/h5-16,18,21-25,35-38,43-45,47-48,50-51,53-57,59,64-66,68,70-71,73-74H,17,19-20,26-34,60-61H2,1-4H3,(H,75,76)/b6-5+,9-7+,10-8+,13-11+,14-12+,18-15+,21-16+/t35?,36?,37?,38-,43?,44?,45?,47?,48?,50?,51?,53?,54+,55-,56+,57?,59?/m1/s1InChIKey
OPGSFDUODIJJGF-JBUZINEHSA-NSmiles
CC(CC(C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 14mg/kg (14mg/kg) | Antibiotics Annual. Vol. 2, Pg. 980, 1954/1955. | |
mouse | LD50 | oral | 1gm/kg (1000mg/kg) | Antibiotiki. Vol. 14, Pg. 932, 1969. | |
mouse | LD50 | subcutaneous | 160mg/kg (160mg/kg) | Progress in Medical Chemistry. Vol. 14, Pg. 105, 1977. | |
rat | LD50 | oral | 2900mg/kg (2900mg/kg) | Antibiotiki. Vol. 14, Pg. 932, 1969. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
log P (octanol-water) | 3.030 | (none) | EST | |
Atmospheric OH Rate Constant | 2.62E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.