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Substance Name: Oxprenolol [INN:BAN]
RN: 6452-71-7
UNII: 519MXN9YZR
InChIKey: CEMAWMOMDPGJMB-UHFFFAOYSA-N
Note
- A beta-adrenergic antagonist used in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety.
Molecular Formula
- C15-H23-N-O3
Molecular Weight
- 265.3507
- All
- Classifications
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- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Adrenergic Agents
- Adrenergic Antagonists
- Adrenergic beta-Antagonists
- Anti-Anxiety Agents
- Anti-Arrhythmia Agents
- Antihypertensive Agents
- Autonomic Agents
- Cardiovascular Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Drug / Therapeutic Agent
- Human Data
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Psychotropic Drugs
- Sympatholytics
- Tranquilizing Agents
- Vasodilator Agents
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Names and Synonyms
Name of Substance
- Oxprenolol
- Oxprenolol [INN:BAN]
MeSH Heading
- Oxprenolol
Synonyms
- (+-)-Oxprenolol
- 1-((1-Methylethyl)amino)-3-(2-(2-propenyloxy)phenoxy)-2-propanol
- 1-(Isopropylamino)-2-hydroxy-3-(o-(allyloxy)phenoxy)propane
- 1-(o-(Allyloxy)phenoxy)-3-(isopropylamino)-2-propanol
- 2-Propanol, 1-((1-methylethyl)amino)-3-(2-(2-propenyloxy)phenoxy)-
- CCRIS 4201
- Coretal
- dl-Oxprenolol
- EINECS 229-257-9
- EINECS 245-359-6
- Osprenololo
- Osprenololo [DCIT]
- Oxprenolol
- Oxprenolol, dl-
- Oxprenololum
- Oxprenololum [INN-Latin]
- UNII-519MXN9YZR
Systematic Names
- (1)-1-(o-(Allyloxy)phenoxy)-3-(isopropylamino)propan-2-ol
- 2-Propanol, 1-((1-methylethyl)amino)-3-(2-(2-propenyloxy)phenoxy)-
- 2-Propanol, 1-(2-allyloxyphenoxy)-3-(isopropylamino)-
- Oxprenolol
Registry Numbers
CAS Registry Number
- 6452-71-7
FDA UNII
- 519MXN9YZR
Other Registry Numbers
- 22972-98-1
- 71186-75-9
Related Registry Number
- 6452-73-9 (hydrochloride)
System Generated Number
- 0006452717
Structure Descriptors
InChI
InChI=1S/C15H23NO3/c1-4-9-18-14-7-5-6-8-15(14)19-11-13(17)10-16-12(2)3/h4-8,12-13,16-17H,1,9-11H2,2-3H3InChIKey
CEMAWMOMDPGJMB-UHFFFAOYSA-NSmiles
CC(C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
human | TDLo | oral | 50mg/kg (50mg/kg) | CARDIAC: PULSE RATE CARDIAC: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | British Medical Journal. Vol. 1, Pg. 776, 1977. |
mouse | LD50 | intraperitoneal | 170mg/kg (170mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Polish Journal of Pharmacology and Pharmacy. Vol. 25, Pg. 145, 1973. |
mouse | LD50 | intravenous | 20mg/kg (20mg/kg) | United States Patent Document. Vol. #5326774, | |
mouse | LD50 | oral | 375mg/kg (375mg/kg) | United States Patent Document. Vol. #5326774, |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
log P (octanol-water) | 2.1 | (none) | EXP | |
Water Solubility | 3180 | mg/L | 25 | EST |
Vapor Pressure | 3.12E-07 | mm Hg | 25 | EST |
Henry's Law Constant | 6.35E-13 | atm-m3/mole | 25 | EST |
Atmospheric OH Rate Constant | 1.60E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.