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Substance Name: Dapiprazole [INN]
RN: 72822-12-9
UNII: 5RNZ8GJO7K
InChIKey: RFWZESUMWJKKRN-UHFFFAOYSA-N

Molecular Formula

  • C19-H27-N5

Molecular Weight

  • 325.4573
 

Classification Codes

  • Adrenergic Agents
  • Adrenergic alpha-Antagonists
  • Adrenergic Antagonists
  • Antipsychotic Agents
  • Central Nervous System Agents
  • Central Nervous System Depressants
  • Drug / Therapeutic Agent
  • Neurotransmitter Agents
  • Psychotropic Drugs
  • Tranquilizing Agents
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Names and Synonyms

Results Name

  • Dapiprazole [INN]

Name of Substance

  • Dapiprazole
  • Dapiprazole [INN]

Synonyms

  • 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine
  • Dapiprazol
  • Dapiprazol [German]
  • Dapiprazole
  • Dapirazol
  • Dapirazol [INN-Spanish]
  • Dapirazolum
  • Dapirazolum [INN-Latin]
  • Glamidolo
  • Remydrial
  • Reversil
  • UNII-5RNZ8GJO7K

Systematic Name

  • 1,2,4-Triazolo(4,3-a)pyridine, 5,6,7,8-tetrahydro-3-(2-(4-(2-methylphenyl)-1-piperazinyl)ethyl)-

Registry Numbers

CAS Registry Number

  • 72822-12-9

FDA UNII

  • 5RNZ8GJO7K

System Generated Number

  • 0072822129

Structure Descriptors

InChI

InChI=1S/C19H27N5/c1-16-6-2-3-7-17(16)23-14-12-22(13-15-23)11-9-19-21-20-18-8-4-5-10-24(18)19/h2-3,6-7H,4-5,8-15H2,1H3

InChIKey

RFWZESUMWJKKRN-UHFFFAOYSA-N

Smiles

Cc1ccccc1N2CCN(CCc3nnc4CCCCn34)CC2

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 260mg/kg (260mg/kg) SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE

BEHAVIORAL: ATAXIA

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Arzneimittel-Forschung. Drug Research. Vol. 32, Pg. 668, 1982.