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Substance Name: Artesunate [USAN:INN:BAN]
RN: 88495-63-0
UNII: 60W3249T9M
InChIKey: FIHJKUPKCHIPAT-AHIGJZGOSA-N

Note

  • A water-soluble, semi-synthetic derivative of the sesquiterpene lactone artemisinin with anti-malarial, anti-schistosomiasis, antiviral, and potential anti-neoplastic activities.

Molecular Formula

  • C19-H28-O8

Molecular Weight

  • 384.4222
 

Classification Codes

  • Amebicides
  • Anthelmintics
  • Anti-Infective Agents
  • Anti-Malarial Therapy
  • Antimalarials
  • Antineoplastic Agents
  • Antiparasitic Agents
  • Antiplatyhelmintic Agents
  • Antiprotozoal Agents
  • Antiviral Agents
  • Schistosomicides
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Names and Synonyms

Name of Substance

  • Artesunate [USAN:INN:BAN]
  • Artesunic acid

MeSH Heading

  • Artesunate

Synonyms

  • 4-Oxo-4-(((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxypyrano(4,3-j)-1,2-benzodioxepin-10-yl hydrogen butanedioate
  • Arinate
  • Armax 200
  • Arsuamoon
  • Arsumax
  • Artesunata
  • Artesunate
  • Artesunato
  • Artesunato [INN-Spanish]
  • Artesunatum
  • Artesunatum [INN-Latin]
  • Artesunic acid
  • Asumax
  • Cosinate
  • Dihydroartemisinine-12alpha-succinate
  • Dihydroqinghasu hemsuccinate
  • Gsunate Forte
  • HSDB 7458
  • Plasmotrin
  • Qinghaozhi
  • Quinghaosu reduced succinate ester
  • Saphnate
  • SM 804
  • Succinyl dihydroartemisinin
  • UNII-60W3249T9M
  • WR 256283
  • Zysunate

Systematic Names

  • (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10-ol, hydrogen succinate
  • Butanedioic acid, mono((3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10-yl) ester

Registry Numbers

CAS Registry Number

  • 88495-63-0

FDA UNII

  • 60W3249T9M

Other Registry Numbers

  • 112346-66-4
  • 1177476-35-5
  • 1236362-31-4
  • 252637-87-9
  • 83507-69-1
  • 91487-94-4

System Generated Number

  • 0088495630

Structure Descriptors

InChI

InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16-,17-,18-,19-/m1/s1

InChIKey

FIHJKUPKCHIPAT-AHIGJZGOSA-N

Smiles

C[C@@H]1CC[C@H]2[C@@H](C)[C@H](OC(=O)CCC(=O)O)O[C@@H]3O[C@@]4(C)CC[C@@H]1[C@@]23OO4