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Substance Name: Thenalidine [INN:BAN]
RN: 86-12-4
UNII: 6U94N2D00F
InChIKey: KLOHYVOVXOUKQI-UHFFFAOYSA-N
Note
- Antihistaminic, antipruritic.
Classification Code
- Antihistaminic
Molecular Formula
- C17-H22-N2-S
Molecular Weight
- 286.441
- All
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
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Names and Synonyms
Name of Substance
- Thenalidine
- Thenalidine [INN:BAN]
Synonyms
- 1-Methyl-4-amino-N-phenyl-N-(2-thenyl)piperidine
- 1-Methyl-4-N-2-thenylanilinopiperidine
- 4-22-00-03760 (Beilstein Handbook Reference)
- AS 716
- BRN 0244448
- EINECS 201-651-5
- Sanbosten
- Tenalidina
- Tenalidina [INN-Spanish]
- Thenalidine
- Thenalidinum
- Thenalidinum [INN-Latin]
- Thenophenopiperidine
- UNII-6U94N2D00F
Systematic Names
- 1-Methyl-4-N-2-thenylanilinopiperidine
- 4-Piperidinamine, 1-methyl-N-phenyl-N-(2-thienylmethyl)- (9CI)
- Piperidine, 1-methyl-4-(N-2-thenylanilino)-
- Thenalidine
Registry Numbers
CAS Registry Number
- 86-12-4
FDA UNII
- 6U94N2D00F
System Generated Number
- 0000086124
Structure Descriptors
InChI
InChI=1S/C17H22N2S/c1-18-11-9-16(10-12-18)19(14-17-8-5-13-20-17)15-6-3-2-4-7-15/h2-8,13,16H,9-12,14H2,1H3InChIKey
KLOHYVOVXOUKQI-UHFFFAOYSA-NSmiles
CN1CCC(CC1)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intravenous | 42mg/kg (42mg/kg) | Annals of Allergy. Vol. 21, Pg. 233, 1963. | |
| mouse | LD50 | oral | 165mg/kg (165mg/kg) | Annals of Allergy. Vol. 21, Pg. 233, 1963. | |
| rabbit | LD50 | intravenous | 20mg/kg (20mg/kg) | Annals of Allergy. Vol. 21, Pg. 233, 1963. | |
| rabbit | LD50 | oral | 430mg/kg (430mg/kg) | Medizinische Welt. Vol. 17, Pg. 2791, 1966. | |
| rat | LD50 | intravenous | 42mg/kg (42mg/kg) | Annals of Allergy. Vol. 21, Pg. 233, 1963. | |
| rat | LD50 | oral | 1060mg/kg (1060mg/kg) | Annals of Allergy. Vol. 21, Pg. 233, 1963. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 96 | deg C | EXP | |
| log P (octanol-water) | 3.890 | (none) | EST | |
| Atmospheric OH Rate Constant | 2.98E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.