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Substance Name: Ceftriaxone [USAN:INN:JAN]
RN: 73384-59-5
UNII: 75J73V1629
InChIKey: VAAUVRVFOQPIGI-SPQHTLEESA-N
Note
- A broad-spectrum cephalosporin antibiotic and cefotaxime derivative with a very long half-life and high penetrability to meninges, eyes and inner ears.
Molecular Formula
- C18-H18-N8-O7-S3
Molecular Weight
- 554.5872
Classification Codes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antibacterial
- Antiviral (COVID-19)
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Names and Synonyms
Results Name
- Ceftriaxone [USAN:INN:JAN]
Name of Substance
- Ceftriaxone
- Ceftriaxone [USAN:INN:JAN]
MeSH Heading
- Ceftriaxone
Synonyms
- Biotrakson
- Ceftriaxona
- Ceftriaxona [INN-Spanish]
- Ceftriaxone
- Ceftriaxone and dextrose in duplex container
- Ceftriaxonum
- Ceftriaxonum [INN-Latin]
- DRG-0071
- EINECS 277-405-6
- Ro 139904
- Rocephin
- UNII-75J73V1629
Systematic Names
- 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio)methyl)-, (6R-(6alpha,7beta(Z)))-
- 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio)methyl)-, (6R,7R)-
- Ceftriaxone
Registry Numbers
CAS Registry Number
- 73384-59-5
FDA UNII
- 75J73V1629
Related Registry Numbers
- 104376-79-6 (di-hydrochloride salt)
- 74578-69-1 (di-hydrochloride salt, hemiheptahydrate)
System Generated Number
- 0073384595
Structure Descriptors
InChI
InChI=1S/C18H18N8O7S3/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32)/b24-8-/t9-,15-/m1/s1InChIKey
VAAUVRVFOQPIGI-SPQHTLEESA-NSmiles
CO\N=C(/C(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
man | TDLo | intramuscular | 14286ug/kg (14.286mg/kg) | BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" LUNGS, THORAX, OR RESPIRATION: DYSPNEA CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) | Allergy. Vol. 55, Pg. 415, 2000. |